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Related Experiment Video

Updated: May 26, 2026

Ex Vivo Infection of Murine Epidermis with Herpes Simplex Virus Type 1

Ex Vivo Infection of Murine Epidermis with Herpes Simplex Virus Type 1

Published on: August 24, 2015

Severe human bocavirus infection, Germany.

Robert Walter Körner¹, Maria Söderlund-Venermo, Silke van Koningsbruggen-Rietschel

¹Children’s Hospital of the University of Cologne, Cologne, Germany. robert.koerner@uk-koeln.de

Emerging Infectious Diseases

|December 17, 2011

Summary

Human bocavirus (HBoV) can cause respiratory illness. This case highlights severe HBoV-induced lower respiratory tract infection in an infant, emphasizing its potential to be life-threatening.

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Area of Science:

Pediatric infectious diseases
Virology
Respiratory medicine

Background:

Human bocavirus (HBoV) is a parvovirus identified in 2005.
HBoV infections are associated with both asymptomatic cases and respiratory illnesses.
The clinical spectrum of HBoV disease requires further elucidation.

Observation:

An 8-month-old infant presented with severe respiratory symptoms.
Symptoms included hypoxia, respiratory distress, wheezing, cough, and fever.
HBoV infection was confirmed as the causative agent.

Findings:

The case confirms HBoV as a pathogen in pediatric respiratory infections.
Severe lower respiratory tract disease was observed in the infected infant.
HBoV infection can manifest with significant clinical severity.

Implications:

This case underscores the potential for HBoV to cause severe, life-threatening lower respiratory tract infections in children.
Highlights the importance of considering HBoV in the differential diagnosis of severe pediatric respiratory illness.
Further research into HBoV pathogenesis and clinical management is warranted.