Bilateral renal myxoid perineuriomas.

Area of Science:

• Oncology
• Neurosurgery
• Pathology

Background:

• Perineuriomas are rare, benign tumors originating from perineurial cells of the peripheral nervous system.
• Typically presenting as extraneural soft tissue masses, they can rarely occur within nerves (intraneural) or in unusual locations.
• Renal perineuriomas are exceptionally uncommon, posing diagnostic challenges due to their rarity and location.

Observation:

• A 25-year-old male presented with large bilateral renal masses.
• Initial diagnostic workup suggested the possibility of renal tumors.
• Biopsy and subsequent histopathological examination confirmed the diagnosis of perineuriomas in both kidneys.

Findings:

• The bilateral renal masses were definitively diagnosed as perineuriomas.
• Surgical excision of both renal perineuriomas was performed.
• Post-operative recovery was uneventful, with no immediate complications.

Implications:

• This case expands the known spectrum of perineurioma presentation, highlighting their potential occurrence in renal locations.
• It underscores the importance of considering rare diagnoses in the differential for renal masses, even when the presentation is atypical.
• Successful surgical management and long-term follow-up demonstrate the viability of operative intervention for renal perineuriomas.