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Related Concept Videos

Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
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Ophthalmic drug delivery faces major limitations due to poor absorption across the corneal membrane. This process is primarily driven by diffusion and is influenced by two main factors: the physicochemical properties of the drug and tear drainage. Most ophthalmic drugs, such as pilocarpine, epinephrine, atropine, and local anesthetics, are weak bases. They are typically formulated at an acidic pH to enhance chemical stability. However, this leads to high ionization, reducing their ability to...
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Related Experiment Video

Updated: May 26, 2026

Intense Pulsed Light for the Treatment of Dry Eye Owing to Meibomian Gland Dysfunction
05:00

Intense Pulsed Light for the Treatment of Dry Eye Owing to Meibomian Gland Dysfunction

Published on: April 1, 2019

Post-LASIK dry eye.

Roni M Shtein1

  • 1Department of Ophthalmology and Visual Sciences, University of Michigan, Kellogg Eye Center, 1000 Wall Street, Ann Arbor, MI 48105, USA, Tel.: +1 734 763 5506.

Expert Review of Ophthalmology
|December 17, 2011
PubMed
Summary
This summary is machine-generated.

Laser-assisted in situ keratomileusis (LASIK) surgery can cause dry eyes. Early identification and perioperative treatment of dry eye disease are crucial for patient satisfaction and visual outcomes after LASIK.

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Area of Science:

  • Ophthalmology
  • Corneal Surgery
  • Dry Eye Disease Pathophysiology

Background:

  • Laser-assisted in situ keratomileusis (LASIK) is a common refractive surgery.
  • Dry eye disease is the most frequent complication following LASIK procedures.
  • Post-LASIK dry eye affects nearly all patients in the immediate postoperative phase.

Purpose of the Study:

  • To highlight the significance of preoperative dry eye identification.
  • To emphasize the importance of perioperative management for dry eye disease.
  • To underscore the impact of dry eye on patient satisfaction and visual outcomes post-LASIK.

Main Methods:

  • Review of current literature on LASIK complications.
  • Analysis of the pathophysiology of dry eye disease in the context of LASIK.
  • Clinical observation of patient outcomes related to dry eye management.

Main Results:

  • Preoperative identification of dry eye is essential for successful LASIK outcomes.
  • Comprehensive perioperative care significantly improves patient satisfaction.
  • Effective management of dry eye disease enhances refractive accuracy after LASIK.

Conclusions:

  • Addressing dry eye disease proactively is key to optimizing LASIK results.
  • Further research into the pathophysiology of post-LASIK dry eye is warranted.
  • Integrated perioperative dry eye management improves the overall LASIK patient experience.