Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Accessory Structures of the Eye01:17

Accessory Structures of the Eye

Optical perception, or vision, is an extraordinary sense dependent on converting light signals received via the ocular organs. These organs, known as eyes, are securely positioned within the bony cavities of the skull, called orbits. The orbits serve a dual purpose: a protective shield for the ocular globes and a stable attachment point for the soft ocular tissues. The eye's external protective mechanisms include the eyelids, which are edged with lashes that act as a barrier against foreign...
Increased Intracranial Pressure ll: Pathophysiology01:29

Increased Intracranial Pressure ll: Pathophysiology

Increased intracranial pressure (ICP) refers to a potentially life-threatening rise in pressure inside the skull. This usually happens when there is a major change in the volume of brain tissue, blood, or cerebrospinal fluid (CSF) — the three components inside the skull. According to the Monro-Kellie doctrine, if the volume of one component increases, the volumes of the other components must decrease to maintain normal pressure. If this does not happen, ICP rises.The process often begins with...
Increased Intracranial Pressure l: Introduction01:14

Increased Intracranial Pressure l: Introduction

Intracranial hypertension is a sustained elevation of intracranial pressure (ICP) above 22 mm Hg. In supine adults, normal ICP is ~7–15 mm Hg.The rigid, nonexpandable cranium contains three components—brain tissue, blood, and cerebrospinal fluid (CSF)—that total ~1,700 mL in a typical adult: 1,400 mL brain (~80%), 150 mL blood (~10%), and 150 mL CSF (~10%). According to the Monro–Kellie doctrine, total intracranial volume is effectively fixed. When one component expands, CSF and venous blood...
Exercise and Cardiac Output01:17

Exercise and Cardiac Output

Regular physical activity is essential for maintaining cardiovascular health, with aerobic exercises being particularly effective. According to the American Heart Association, 150 minutes of moderate to intense aerobic exercise per week is recommended for a healthy heart. Aerobic activities may include brisk walking, running, bicycling, cross-country skiing, and swimming, ideally performed three to five times per week.
Sustained exercise increases the muscles' oxygen demand, which can be met...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Corrected Percentile Curves to Track Myopisation-The Anyang Childhood Eye Study.

Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)·2026
Same author

Trabeculotome Tunneling Trabeculoplasty (3T): A Step-by-step Surgical Protocol for Primary Open-angle Glaucoma.

Journal of visualized experiments : JoVE·2026
Same author

Goniosynechialysis under a microscope alone and under direct gonioscopy for chronic angle-closure glaucoma patients coexisted with cataract.

International journal of ophthalmology·2026
Same author

Light intensity and light/dark cycles regulate refractive development and myopia in mice through circadian rhythm-related genes.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie·2026
Same author

Response to comments on "Circadian rhythm disruption induces myopia in mice".

Experimental eye research·2026
Same author

The Light-Eye-Brain Axis: Neurobiological Links Between Mood Disorders and Myopia-A Narrative Review.

Ophthalmology and therapy·2026
Same journal

[The era of precision diagnosis and treatment for optic neuritis: advances in diagnostic classification, biomarkers and therapeutic strategies].

[Zhonghua yan ke za zhi] Chinese journal of ophthalmology·2026
Same journal

[Application value of ocular multimodal imaging methods in the evaluation of increased intracranial pressure].

[Zhonghua yan ke za zhi] Chinese journal of ophthalmology·2026
Same journal

[Secondary panuveitis after ocular wasp sting: a case report].

[Zhonghua yan ke za zhi] Chinese journal of ophthalmology·2026
Same journal

[Correlation of ocular surface changes with filtering bleb morphology after antiglaucoma surgery for primary angle-closure glaucoma].

[Zhonghua yan ke za zhi] Chinese journal of ophthalmology·2026
Same journal

[Regulation of SARM1 on SNPH expression and its participation in glaucomatous optic neuropathy].

[Zhonghua yan ke za zhi] Chinese journal of ophthalmology·2026
Same journal

[Construction of a regulated <i>Crat</i> overexpression system in mouse hippocampal neuronal HT22 cell line].

[Zhonghua yan ke za zhi] Chinese journal of ophthalmology·2026
See all related articles

Related Experiment Video

Updated: May 26, 2026

Trabecular Meshwork Response to Pressure Elevation in the Living Human Eye
09:03

Trabecular Meshwork Response to Pressure Elevation in the Living Human Eye

Published on: June 20, 2015

[Physical exercise and intraocular pressure].

Yuan-bo Liang1, Yue Wu, Si-zhen Li

  • 1Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, China. yuanboliang@gmail.com

[Zhonghua Yan Ke Za Zhi] Chinese Journal of Ophthalmology
|December 20, 2011
PubMed
Summary
This summary is machine-generated.

Physical exercise may help lower intraocular pressure (IOP) in glaucoma patients. While the exact mechanisms are complex and vary, activities like jogging and walking show potential as complementary glaucoma therapies.

More Related Videos

Translaminar Autonomous System Model for the Modulation of Intraocular and Intracranial Pressure in Human Donor Posterior Segments
08:55

Translaminar Autonomous System Model for the Modulation of Intraocular and Intracranial Pressure in Human Donor Posterior Segments

Published on: April 24, 2020

A Model of Glaucoma Induced by Circumlimbal Suture in Rats and Mice
07:00

A Model of Glaucoma Induced by Circumlimbal Suture in Rats and Mice

Published on: October 5, 2018

Related Experiment Videos

Last Updated: May 26, 2026

Trabecular Meshwork Response to Pressure Elevation in the Living Human Eye
09:03

Trabecular Meshwork Response to Pressure Elevation in the Living Human Eye

Published on: June 20, 2015

Translaminar Autonomous System Model for the Modulation of Intraocular and Intracranial Pressure in Human Donor Posterior Segments
08:55

Translaminar Autonomous System Model for the Modulation of Intraocular and Intracranial Pressure in Human Donor Posterior Segments

Published on: April 24, 2020

A Model of Glaucoma Induced by Circumlimbal Suture in Rats and Mice
07:00

A Model of Glaucoma Induced by Circumlimbal Suture in Rats and Mice

Published on: October 5, 2018

Area of Science:

  • Ophthalmology
  • Exercise Physiology
  • Glaucoma Research

Context:

  • Since the 1960s, a link between physical activity and reduced intraocular pressure (IOP) in glaucoma patients has been noted.
  • The extent of IOP reduction is influenced by exercise type, intensity, and post-exercise duration.
  • Variations in IOP-lowering effects exist between glaucoma patients and healthy individuals.

Purpose:

  • To explore the observed effects of physical exercise on intraocular pressure (IOP) in glaucoma management.
  • To summarize the known and hypothesized mechanisms behind exercise-induced IOP reduction.
  • To assess the potential of physical exercise as an adjunct therapy for glaucoma.

Summary:

  • Physical exercise, including jogging, walking, and cycling, has demonstrated the ability to decrease intraocular pressure (IOP).
  • The underlying mechanisms are multifaceted, potentially involving norepinephrine levels, colloid osmotic pressure, nitric oxide/endothelin interactions, and genetic factors like β2-adrenergic receptor polymorphism.
  • Despite incomplete understanding, exercise is considered a viable complementary approach alongside traditional glaucoma treatments.

Impact:

  • Highlights the potential of non-pharmacological interventions in managing glaucoma.
  • Encourages further research into the precise physiological pathways of exercise-induced IOP reduction.
  • Supports the integration of physical activity into comprehensive glaucoma care plans.