Related Experiment Video
Updated: May 26, 2026

07:27
Anterior Segment Organ Culture Platform for Tracking Open Globe Injuries and Therapeutic Performance
Published on: August 25, 2021
Prognostic factors influencing final visual acuity in open globe injuries
Ozlem Yalcin Tök1, Levent Tok, Elif Eraslan
1Department of Ophthalmology, Faculty of Medicine, Süleyman Demirel University, Isparta, Turkey. esattok@yahoo.com
The Journal of Trauma
|December 21, 2011
Summary
Poor initial visual acuity (VA), retinal detachment, and vitreous prolapse significantly impact final VA outcomes in open globe injuries. Understanding these factors is crucial for patient prognosis and treatment planning.
Area of Science:
- Ophthalmology
- Trauma Surgery
Background:
- Open globe injuries represent a significant cause of vision loss.
- Identifying factors influencing final visual acuity (VA) is critical for patient management.
Purpose of the Study:
- To investigate key factors affecting final visual acuity in patients with open globe injuries.
- To inform prognosis and guide clinical decision-making for open globe injuries.
Main Methods:
- Retrospective review of 313 patients with open globe injuries followed for over 6 months.
- Data collected included demographics, initial VA, injury characteristics, and final best-corrected VA.
- Statistical analysis employed univariate and multiple logistic regression models.
Main Results:
- Penetrating injuries, often work-related, were most common.
- Univariate analysis identified age, injury zone, blunt/rupture types, poor initial VA, endophthalmitis, retinal detachment, relative afferent papillary defect, hyphema, and prolapse as contributing factors.
- Multiple logistic regression revealed poor initial VA, retinal detachment, and vitreous prolapse as statistically significant predictors of final VA.
Conclusions:
- Initial visual acuity, retinal detachment, and vitreous prolapse are the most critical factors influencing final visual acuity in open globe injuries.
- These findings are vital for accurate prognosis and treatment strategies in managing ocular trauma.
Related Concept Videos
Glaucoma: Overview
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Open Angle Glaucoma: Treatment
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
Angle Closure Glaucoma: Treatment
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
Photoreceptors and Visual Pathways
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category, whereas...
