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Updated: May 26, 2026

06:19
High-Throughput Screening to Obtain Crystal Hits for Protein Crystallography
Published on: March 10, 2023
Crystal cookery - using high-throughput technologies and the grocery store as a teaching tool
Summary
This study introduces a novel educational program using crystal growth and accessible materials to teach scientific methods. It offers remote students valuable research experience, bridging resource gaps.
Area of Science:
- Crystallography
- Materials Science
- Chemical Education
Background:
- Crystallography provides atomic-scale insights across science and engineering.
- Crystal growth is a key component of crystallography and an effective educational tool.
- Existing methods utilize 'grocery store chemistry' and remote-access screening.
Purpose of the Study:
- To describe the development of an educational program focused on crystal growth.
- To demonstrate how accessible materials can facilitate scientific method education.
- To explore the potential for linking this program with broader crystallography research.
Main Methods:
- Utilizing a 'grocery store chemistry' approach for crystallization experiments.
- Integrating high-throughput remote-access screening technologies.
- Developing and prototyping procedures with student involvement.
Main Results:
- The program effectively teaches the scientific method.
- It accommodates diverse educational levels and remote access.
- Preliminary analyses show promising results for student engagement.
Conclusions:
- This educational approach bridges the gap for students in remote or underfunded locations.
- It provides international-level research experience using accessible resources.
- The program has the potential to broaden participation in crystallography.
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