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Pulmonary Embolism I: Introduction01:29

Pulmonary Embolism I: Introduction

Pulmonary embolism (PE) occurs when a thrombus, fat or air embolus, amniotic fluid, or tumor tissue blocks one or more pulmonary arteries. These blockages originate in the venous system or the right side of the heart.EtiologyPE primarily arises from deep vein thrombosis (DVT) and other hypercoagulable states, such as inherited thrombophilias. Additional etiological factors include venous stasis, commonly seen in obesity, and endothelial injury from surgery and trauma. Less common causes include...
Pulmonary Embolism I: Introduction01:19

Pulmonary Embolism I: Introduction

A blood clot, or thrombus, is a semi-solid mass composed of fibrin, platelets, and red blood cells. When it forms within a vessel, it can obstruct blood flow, known as thrombosis. If part of the clot detaches, it becomes an embolus that can travel and block distant vessels. When this occurs in the pulmonary arteries, it causes a condition known as pulmonary embolism (PE).Origin and ImpactMost often, the embolus originates from a thrombus in the deep veins of the lower limbs, a condition called...
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care01:29

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
Pulmonary Embolism III: Nursing Management01:27

Pulmonary Embolism III: Nursing Management

A pulmonary embolism occurs when a thrombus, amniotic fluid, tumor tissue, fat, or air embolus blocks one or more pulmonary arteries. Effective nursing management and patient education are crucial for improving outcomes and preventing recurrence.Nursing management starts with obtaining a comprehensive patient history, particularly noting any history of deep vein thrombosis (DVT). Assess for clinical manifestations, including dyspnea, chest pain, crackles, heart murmurs, and signs of right-sided...
Pulmonary Cycle: Exhalation01:17

Pulmonary Cycle: Exhalation

In terms of human respiration, the act of expelling air, known as exhalation (or expiration), operates on the principle of pressure gradients. During expiration, the pressure within the lungs exceeds that of the surrounding atmosphere. Under normal conditions, quiet breathing involves passive exhalation and is free of muscular contractions. This is because the exhalation process is driven by the natural elastic recoil of the lungs and chest wall, both of which have an inherent tendency to...
Pneumothorax-I01:26

Pneumothorax-I

A pneumothorax is a condition where air builds up in the space between the lung and the chest wall, causing the lung to collapse. This condition arises when air enters the space between the parietal and visceral pleura, disrupting the negative pressure essential for lung inflation. This can lead to a partial or complete collapse of the lung.
Pneumothorax can be even further classified as spontaneous, traumatic, and tension pneumothorax.

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Updated: May 26, 2026

A Porcine Model of Acute Autologous Pulmonary Embolism
07:44

A Porcine Model of Acute Autologous Pulmonary Embolism

Published on: September 6, 2024

Pulmonary embolism in children.

Leonardo R Brandão1, Veerle Labarque, Yaser Diab

  • 1Department of Paediatrics, Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, Ontario, Canada. leonardo.brandao@sickkids.ca).

Seminars in Thrombosis and Hemostasis
|December 22, 2011
PubMed
Summary

Pediatric pulmonary embolism (PE) diagnosis and treatment often use adult protocols. This review examines historical progress and current knowledge gaps in childhood PE, highlighting epidemiology and diagnostic tools.

Related Experiment Videos

Last Updated: May 26, 2026

A Porcine Model of Acute Autologous Pulmonary Embolism
07:44

A Porcine Model of Acute Autologous Pulmonary Embolism

Published on: September 6, 2024

Area of Science:

  • Pediatric Medicine
  • Cardiovascular Diseases
  • Pulmonary Medicine

Background:

  • Pulmonary embolism (PE) is increasingly recognized in children.
  • Current diagnostic and therapeutic algorithms for pediatric PE are largely adapted from adult protocols.
  • There is a need for a pediatric-specific understanding of PE.

Purpose of the Study:

  • To review the historical progression of pulmonary embolism (PE) in children.
  • To contextualize pediatric PE advancements alongside key events in adult PE.
  • To highlight current knowledge gaps in pediatric PE.

Main Methods:

  • Literature review of historical pediatric reports on PE.
  • Analysis of national database reports to characterize pediatric PE epidemiology.
  • Review of diagnostic tools applicable to children with PE.

Main Results:

  • Initial pediatric PE reports and their evolution are summarized.
  • Epidemiological data from national databases provide insights into childhood PE.
  • Specific diagnostic considerations for pediatric PE are discussed.

Conclusions:

  • Significant progress has been made in understanding pediatric PE.
  • Current management strategies require further adaptation for the pediatric population.
  • Further research is needed to address knowledge gaps in pediatric PE therapy and outcomes.