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[PsyCoLaus: mental disorders and cardiovascular diseases: spurious association?]
M Preisig1, G Waeber, V Mooser
1Centre d'épidémiologie psychiatrique et de psychopathologie, Départment de psychiatrie CHUV, Site de Cery, 1008 Prilly. martin.preisig@chuv.ch
Insights
This study investigates the links between mental disorders and cardiovascular diseases (CVD) and their risk factors (CVRF). Understanding these connections can improve prevention and treatment strategies for both conditions.
Area of Science:
- Psychiatry and Cardiology
- Epidemiology
- Longitudinal Studies
Context:
- Cardiovascular diseases (CVD), their risk factors (CVRF), and mental disorders are highly prevalent.
- Co-occurrence of mental disorders and CVD/CVRF is more frequent than chance suggests.
- Underlying mechanisms linking these conditions remain poorly understood.
Purpose:
- To determine if mental disorders increase vulnerability to CVRF and CVD.
- To investigate if CVRF and CVD promote the development of mental disorders.
- To explore shared pathogenetic processes between CVRF/CVD and mental disorders.
Summary:
- The PsyCoLaus study, the psychiatric component of CoLaus, integrates comprehensive psychiatric evaluations with existing CoLaus data.
- This longitudinal project aims to elucidate the bidirectional relationship between mental health and cardiovascular health.
- Key research questions address causality and shared pathways.
Impact:
- Enhanced understanding of psychological, physiological, and behavioral links between mental disorders and CVD/CVRF.
- Development of more targeted and effective prevention and treatment strategies for both psychiatric and cardiovascular conditions.
- Reduction of the significant global burden of disease associated with these co-occurring conditions.
Abstract:
Cardio-vascular diseases (CVD), their well established risk factors (CVRF) and mental disorders are common and co-occur more frequently than would be expected by chance. However, the mechanisms underlying this association are still poorly understood. The main study questions of PsyCoLaus, the psychiatric arm of CoLaus, are: 1) Do mental disorders increase vulnerability to CVRF and CVD? 2) Do CVRF and CVD promote the development of mental disorders? 3) Do CVRF/ CVD and mental disorders share common pathogenetic processes? The longitudinal project adds a comprehensive psychiatric evaluation to the CoLaus investigation. A better understanding of the psychological, physiological and behavioral links underlying CVD/ CVRF and mental disorders will result in the development of more specific and efficient strategies of prevention and treatment for both psychiatric and CVD/CVRF, two major elements of burden of disease.
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