Related Experiment Video
Updated: Apr 3, 2026

Marble Burying and Nestlet Shredding as Tests of Repetitive, Compulsive-like Behaviors in Mice
Published on: December 24, 2013
[Perspectives on obsessive-compulsive spectrum disorders and its trends for the revision of DSM-5]
1Department of Neuropsychiatry, Hyogo College of Medicine.
Abstract:
In the process of revising of DSM-5 for release in 2013, there is growing interest in the concept of a nosologically distinct spectrum of obsessive-compulsive disorders (OCSDs). Validity and compass of this spectrum remains to be fully elucidated, but a preliminary approach emphasizes that putative OCSDs have phenomenologic (eg. repetitive thoughts and/ or behaviors), etiological, psychobiologic or treatment overlap with OCD. Studies have investigated the relevant neurocircuitry, neurochemistry, and neuroendocrinology underlying anxiety disorders and OCSDs, and have explored the underlying genetic basis of and relevant intermediate phenotypes for developing these conditions. There appears to be some scientific validity and clinical utility for conceptualizing a subgroup of emotional-related disorders, within which fall the anxiety, posttraumatic, and OCSDs. However OCSDs, especially motoric OCSDs such as tic or Tourette's disorder still remain controversial; the appropriate grouping of these is still under discussion and may still change.
More Related Videos
Related Concept Videos
Anxiety: Overview
Individuals with anxiety often experience a range of physical and emotional symptoms, including sweating, trembling, tachycardia, and disturbances in sleep patterns. These symptoms vary in intensity and frequency but are generally disruptive and distressing.
Theoretical Approaches to Psychological Disorder
Biological approach
The biological approach posits that internal, organic factors are the primary causes of such disorders. This perspective emphasizes brain structure and function, genetic predispositions, and neurotransmitter imbalances. For example, schizophrenia has been associated with both genetic...
Diagnostic and Statistical Manual of Mental Disorders (DSM)
Obsessive-Compulsive Disorder
Personality Disorders: Dependent and Obsessive-Compulsive
Dependent Personality Disorder
Dependent personality disorder is characterized by an excessive reliance on others to manage various aspects of life. Individuals with this disorder often struggle...
Oppositional Defiant Disorder
Diagnostic Criteria and...

