Related Experiment Videos
[Primary empty sella associated with peripheral endocrine deficiency: two cases (author's transl)].
La Nouvelle Presse Medicale
|May 12, 1979
Summary
A large sella turcica with persistent high ACTH and TSH levels, initially thought to be reactive hypersecretion, was found to be primary empty sella syndrome in endocrine insufficiency cases.
Area of Science:
- Endocrinology
- Radiology
- Pathology
Background:
- Investigating radiological findings in patients with long-standing peripheral endocrine insufficiency.
- Examining cases with a large sella turcica and persistently elevated plasma ACTH and TSH levels despite hormone therapy.
Observation:
- Radiological evidence of a large sella turcica was noted in two patients with endocrine disorders.
- Elevated adrenocorticotropic hormone (ACTH) and thyroid-stimulating hormone (TSH) levels persisted despite treatment.
Findings:
- Scanner studies and pathological examination revealed primary empty sella syndrome.
- This contrasts with the initial hypothesis of reactive hypersecretion of pituitary stimulins.
Implications:
- Primary empty sella syndrome can manifest with radiological findings mimicking reactive pituitary hyperplasia.
- Understanding this distinction is crucial for accurate diagnosis and management of endocrine disorders.