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Related Concept Videos

Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Metastasis02:30

Metastasis

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Epithelial-to-Mesenchymal Transition
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Osteoclasts in Bone Remodeling01:31

Osteoclasts in Bone Remodeling

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Cellular Adaptation IV: Dysplasia and Metaplasia01:24

Cellular Adaptation IV: Dysplasia and Metaplasia

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Related Experiment Videos

Ameloblastic carcinoma.

Hari Ram, Shadab Mohammad, Nuzhat Husain

    Journal of Maxillofacial and Oral Surgery
    |December 23, 2011
    PubMed
    Summary
    This summary is machine-generated.

    Ameloblastic carcinoma (AC) is a rare, aggressive odontogenic tumor. Wide local excision is the primary treatment, with selective lymph node dissection and close follow-up being crucial for managing this malignancy.

    Keywords:
    Ameloblastic carcinomaAmeloblastomaOdontogenic tumor

    Related Experiment Videos

    Area of Science:

    • Oral pathology
    • Oncology
    • Maxillofacial surgery

    Background:

    • Ameloblastic carcinoma (AC) is a rare malignant epithelial odontogenic tumor.
    • It predominantly affects the maxillofacial skeleton, particularly the mandible.
    • AC can arise de novo or from pre-existing ameloblastoma or odontogenic cysts.

    Observation:

    • AC presents with cytological features of both ameloblastoma and carcinoma.
    • Clinical presentation varies from cystic lesions to large masses with ulceration and bone resorption.
    • The tumor exhibits aggressive behavior with local destruction, lymph node involvement, and metastasis.

    Findings:

    • Wide local excision is the recommended treatment for ameloblastic carcinoma.
    • Selective regional lymph node dissection is considered based on clinical factors.
    • Radiotherapy and chemotherapy have a limited role in AC management.

    Implications:

    • Early diagnosis and aggressive surgical management are vital for AC.
    • Close, long-term patient monitoring is essential due to the tumor's aggressive nature.
    • Further research may explore targeted therapies for ameloblastic carcinoma.