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Updated: May 26, 2026
05:07
Multimodality Diagnosis of Mesenteric Ischemia
Published on: July 21, 2023
Mesenteric panniculitis. Part 1: MDCT--pictorial review
1Department of Diagnostic Radiology, Clinique St Luc, Bouge, Belgium. bcoulier@skynet.be
Summary
Mesenteric panniculitis (MP) is a rare benign inflammatory condition. MDCT imaging reveals characteristic signs like mass effect and a fatty halo, aiding diagnosis and differentiating it from tumors.
Area of Science:
- Radiology
- Gastroenterology
- Pathology
Background:
- Mesenteric panniculitis (MP) is an uncommon, benign inflammatory condition of mesenteric adipose tissue.
- Varied terminology and unclear etiology cause diagnostic confusion; preferred histopathological term is sclerosing mesenteritis.
- MP and retractile mesenteritis (RM) represent pathological subgroups, with MP characterized by inflammation/fat necrosis and RM by fibrosis/retraction.
Purpose of the Study:
- To illustrate the characteristic multi-detector computed tomography (MDCT) findings of Mesenteric Panniculitis (MP).
- To review the literature and discuss the differential diagnosis of MP.
- To highlight key imaging signs for radiological diagnosis of MP.
Main Methods:
- Retrospective analysis of 64-row MDCT scans from a 5-year case collection of MP.
- Illustration of characteristic MDCT findings.
- Literature review for differential diagnosis discussion.
Main Results:
- Classical CT signs for MP diagnosis include: mass effect, inhomogeneous higher attenuation of mesenteric fat, soft tissue nodes, a hypoattenuated fatty halo sign, and an hyperattenuating pseudocapsule.
- The halo sign and pseudocapsule are inconstant but highly specific.
- Absence of histological verification is a study limitation.
Conclusions:
- MDCT findings are crucial for diagnosing MP, differentiating it from other mesenteric disorders.
- Differential diagnosis is extensive, including lymphoma, liposarcoma, and carcinomatosis.
- PET/CT can help exclude tumoral involvement; MP generally has a favorable prognosis.
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