Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Modeling stable and dynamic vulnerabilities in suicide risk: A mechanistic test of fluid vulnerability theory in military personnel with suicidal ideation.

Behaviour research and therapy·2026
Same author

Suicidal ideation and its evaluation: A systematic review and validation of the MEntal states related to Suicidal Ideation Scale (MESIS).

Journal of affective disorders·2026
Same author

Lighting the path: a narrative review of non-molecular intraoperative lung imaging modalities.

Journal of thoracic disease·2026
Same author

Rapid Quantitative Imaging of Heterogeneous Tissue Hemoglobin Dynamics Using Spatial Frequency Domain Imaging.

Journal of vascular research·2026
Same author

Optical and acoustic scattering in cutaneous neurofibromas: Implications for early detection.

The Journal of investigative dermatology·2026
Same author

The effect of non-invasive transcranial focused ultrasound for depression on the default mode network: an open-label pilot trial.

Frontiers in psychiatry·2026
Same journal

Segmentation-guided photon pooling enables robust single-cell analysis and fast fluorescence lifetime imaging microscopy.

Journal of biomedical optics·2026
Same journal

Method of spatial scanning of modulated laser radiation for outline imaging of interphalangeal joints.

Journal of biomedical optics·2026
Same journal

Multimodal optical imaging for the assessment of the teratogenic effects of ethanol on zebrafish development.

Journal of biomedical optics·2026
Same journal

Fluorescence properties of collagen types I-V: a comprehensive study of spectral and lifetime characteristics.

Journal of biomedical optics·2026
Same journal

Spectral dependence of lipofuscin fluorescence lifetimes revealed by FLIM with a superconducting nanowire single-photon detector.

Journal of biomedical optics·2026
Same journal

Building the future of biophotonics through experiential education and seasonal schools.

Journal of biomedical optics·2026
See all related articles

Related Experiment Video

Updated: May 26, 2026

Measuring Spatially- and Directionally-varying Light Scattering from Biological Material
11:57

Measuring Spatially- and Directionally-varying Light Scattering from Biological Material

Published on: May 20, 2013

Imaging scattering orientation with spatial frequency domain imaging.

Soren D Konecky1, Tyler Rice, Anthony J Durkin

  • 1University of California, Irvine, Beckman Laser Institute and Medical Clinic, Laser Microbeam and Medical Program (LAMMP), 1002 Health Sciences Road, Irvine, California 92612, USA.

Journal of Biomedical Optics
|December 24, 2011
PubMed
Summary
This summary is machine-generated.

This study introduces a new optical imaging method to detect the orientation of microscopic structures within tissues. The technique uses structured light reflectance to visualize directional scattering, improving contrast in biological samples.

More Related Videos

Time Multiplexing Super Resolving Technique for Imaging from a Moving Platform
06:25

Time Multiplexing Super Resolving Technique for Imaging from a Moving Platform

Published on: February 12, 2014

A Guide to Structured Illumination TIRF Microscopy at High Speed with Multiple Colors
11:15

A Guide to Structured Illumination TIRF Microscopy at High Speed with Multiple Colors

Published on: May 30, 2016

Related Experiment Videos

Last Updated: May 26, 2026

Measuring Spatially- and Directionally-varying Light Scattering from Biological Material
11:57

Measuring Spatially- and Directionally-varying Light Scattering from Biological Material

Published on: May 20, 2013

Time Multiplexing Super Resolving Technique for Imaging from a Moving Platform
06:25

Time Multiplexing Super Resolving Technique for Imaging from a Moving Platform

Published on: February 12, 2014

A Guide to Structured Illumination TIRF Microscopy at High Speed with Multiple Colors
11:15

A Guide to Structured Illumination TIRF Microscopy at High Speed with Multiple Colors

Published on: May 30, 2016

Area of Science:

  • Biomedical Optics
  • Medical Imaging
  • Light Scattering

Background:

  • Traditional optical imaging struggles with sensitivity to light scattering structure orientation.
  • Imaging microscopic structures in scattering media like biological tissues is challenging.
  • Existing methods lack the ability to differentiate between isotropic and anisotropic scattering.

Purpose of the Study:

  • To develop a novel spatial frequency domain method for imaging contrast from oriented scattering structures.
  • To measure the angular-dependence of structured light reflectance for enhanced imaging.
  • To introduce a new contrast function sensitive to directional light scattering.

Main Methods:

  • Projecting sinusoidal light patterns and measuring pattern blurring as a function of projection angle.
  • Deriving a spatial Fourier domain solution to an anisotropic diffusion model.
  • Introducing a scattering orientation index (SOI) based on reflectance measurements.

Main Results:

  • The scattering orientation index (SOI) is independent of bulk scattering and absorption.
  • Isotropic and oriented scattering structures can be clearly distinguished.
  • Subsurface microscopic scattering structures up to 600 μm deep were oriented in highly scattering material.

Conclusions:

  • The developed spatial frequency domain method effectively images oriented scattering structures.
  • The scattering orientation index (SOI) provides robust contrast for directional scattering.
  • This technique offers improved subsurface imaging of microstructural orientation in biological tissues.