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Related Concept Videos

Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...

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Related Experiment Video

Updated: May 26, 2026

Lung Rapid Recovery Procurement Combined with Abdominal Normothermic Regional Perfusion in Controlled Donation after Circulatory Death
09:54

Lung Rapid Recovery Procurement Combined with Abdominal Normothermic Regional Perfusion in Controlled Donation after Circulatory Death

Published on: August 15, 2022

Donation after circulatory death.

A R Manara1, P G Murphy, G O'Callaghan

  • 1The Intensive Care Unit, Frenchay Hospital, Frenchay Park Road, Bristol BS16 1LE, UK. alex.manara@nbt.nhs.uk

British Journal of Anaesthesia
|December 24, 2011
PubMed
Summary
This summary is machine-generated.

Donation after circulatory death (DCD) is crucial for organ transplantation due to organ shortages. DCD involves organ retrieval after death is confirmed by circulatory criteria, expanding beyond kidneys to organs like the liver and lungs.

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Last Updated: May 26, 2026

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Large-Animal Model of Donation after Circulatory Death and Normothermic Regional Perfusion for Cardiac Assessment

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Area of Science:

  • Medical Science
  • Transplantation Medicine
  • Bioethics

Background:

  • The persistent shortage of organs for transplantation necessitates exploring alternative donation models.
  • Donation after circulatory death (DCD) is re-emerging as a vital source for organs, including kidneys, liver, pancreas, and lungs.
  • DCD differs significantly from the standard donation after brain death model.

Purpose of the Study:

  • To discuss the challenges and ethical considerations in implementing DCD programs.
  • To highlight the growing professional consensus on the ethical and legal justification of DCD interventions.
  • To explore the integration of DCD into routine end-of-life care.

Main Methods:

  • Review of current practices and ethical frameworks for DCD.
  • Analysis of the challenges in identifying suitable DCD donors and managing warm ischaemia.
  • Examination of professional, ethical, and legal aspects of DCD.

Main Results:

  • DCD is increasingly utilized for various organs beyond kidneys, despite challenges like warm ischaemia.
  • Professional consensus is growing regarding the ethical and legal acceptability of DCD interventions.
  • In some nations, DCD constitutes a significant portion of deceased organ donors, becoming part of end-of-life care.

Conclusions:

  • DCD is a critical strategy to address organ shortages for transplantation.
  • Addressing challenges in donor identification and ischaemia management is key to successful DCD programs.
  • The integration of DCD into end-of-life care signifies a shift towards routine organ donation practices.