Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pharmacovigilance01:19

Pharmacovigilance

Post-marketing surveillance is a critical component of pharmaceutical regulation, often uncovering unanticipated adverse drug reactions (ADRs) once a drug is widely used over an extended period.
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
Therapeutic Drug Monitoring: Drug Analysis Methods01:26

Therapeutic Drug Monitoring: Drug Analysis Methods

Therapeutic Drug Monitoring (TDM) is a clinical practice that measures specific drug levels in a patient's blood or body tissues to tailor drug therapy effectively. This monitoring is critical for managing drugs with narrow therapeutic indices like digoxin and phenytoin, ensuring they are both safe and effective. For instance, monitoring theophylline levels in asthma patients involves precision and sensitivity to adjust doses according to individual responses to therapy, ensuring efficacy and...
Drug Regulation01:25

Drug Regulation

Drug regulation encompasses the management of drug usage by evaluating its safety and efficacy through assessments conducted by regulatory authorities. Regrettably, the history of drug regulation is marred by several catastrophic events. One such incident is the Elixir Sulfanilamide tragedy, in which the toxic compound diethyl glycol was included in a sweet-tasting medication, leading to numerous fatalities. This event prompted the enactment of the Food, Drug, and Cosmetic Act in 1938. Under...
Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
Therapeutic Drug Monitoring: Overview and Classification01:16

Therapeutic Drug Monitoring: Overview and Classification

Therapeutic Drug Monitoring (TDM) is a clinical practice that measures specific drug levels in a patient's blood at designated intervals to ensure the drug concentration stays within a therapeutic range. This monitoring is crucial for optimizing individual dosage regimens, enhancing therapeutic efficacy, and minimizing drug-related toxicity. TDM is vital for drugs with narrow therapeutic windows, significant variability in pharmacokinetics, and a clear correlation between plasma levels and...
Drug Dosage Regimen: Overview01:15

Drug Dosage Regimen: Overview

A drug dosage regimen describes the specific instructions and schedule for administering a drug to a patient. It considers factors such as drug dosage, frequency, route of administration, and duration of treatment. Designing an appropriate dosage regimen for a patient aims to achieve a target drug concentration at the site of action.
Typically, the starting dose and dosing interval are guided by the manufacturer's recommendations based on clinical trials conducted during and after drug...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

REPEAT BP: Reviewing Effective Practices for Elevating Adherence in Treatment of Hypertension.

AMIA ... Annual Symposium proceedings. AMIA Symposium·2026
Same author

Time-series Machine Learning Models to Support Emergency Department Operational Planning.

AMIA ... Annual Symposium proceedings. AMIA Symposium·2026
Same author

A Comprehensive Approach for Assessing the Impact of Ambient Documentation.

AMIA ... Annual Symposium proceedings. AMIA Symposium·2026
Same author

Properties of PVA, Chitosan, and Collagen Solutions and Their Role in Electrospinning: Insights from Simulations and Experiments.

The journal of physical chemistry. B·2025
Same author

Effects of Hydroxylation and Packing Geometry on Tropocollagen Stability: Insights from Molecular Dynamics Simulations.

The journal of physical chemistry. B·2025
Same author

Investigation and optimization of DNA isolation efficiency using ferrite-based magnetic nanoparticles.

Biotechnology reports (Amsterdam, Netherlands)·2025

Related Experiment Video

Updated: May 26, 2026

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
11:17

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses

Published on: August 30, 2018

Evaluation of medication list completeness, safety, and annotations.

Michael C Owen1, Nancy M Chang, David H Chong

  • 1Columbia University, New York, NY, USA.

AMIA ... Annual Symposium Proceedings. AMIA Symposium
|December 24, 2011
PubMed
Summary

Medication lists often lack crucial details like dosage or frequency, potentially harming patients. Enhancing electronic tools to support flexible annotations is key for improving medication list completeness and patient safety.

Related Experiment Videos

Last Updated: May 26, 2026

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
11:17

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses

Published on: August 30, 2018

Area of Science:

  • Clinical Informatics
  • Patient Safety
  • Health Informatics

Background:

  • Clinical documents commonly include patient medication lists.
  • Incomplete medication information (dose, route, frequency) can hinder communication and patient safety.
  • Annotations on medication lists are frequently used by clinicians.

Purpose of the Study:

  • To assess the completeness of medication lists in clinical documents.
  • To identify the prevalence and potential harm of missing medication information.
  • To analyze the content and utility of annotations on medication lists.

Main Methods:

  • Review of 253 medication lists from clinical documents.
  • Physician reviewers assessed missing information and potential harm.
  • Thematic analysis of annotations present in the medication lists.

Main Results:

  • 72% of medication lists had at least one missing dose, route, or frequency.
  • 19% of lists contained missing information deemed potentially harmful.
  • 22% of lists included annotations, most commonly related to medical history, treatment changes, or adherence.

Conclusions:

  • A significant proportion of medication lists lack essential details, posing potential risks.
  • Annotations are a common feature, offering valuable contextual information.
  • Future electronic medication reconciliation tools should incorporate flexible annotation capabilities to improve completeness and usability.