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Updated: May 26, 2026
Continuous Venous-Arterial Doppler Ultrasound During a Preload Challenge
Published on: January 20, 2023
Hemodynamic changes during a deep inspiration maneuver predict fluid responsiveness in spontaneously breathing
Sébastien Préau1, Florent Dewavrin, Vincent Soland
1Service de Réanimation Polyvalente, Centre Hospitalier Jean Bernard, Avenue Désandrouin, 59300 Valenciennes, France.
Objective:
We hypothesized that the hemodynamic response to a deep inspiration maneuver (DIM) indicates fluid responsiveness in spontaneously breathing (SB) patients.
Design:
Prospective study.
Setting:
ICU of a general hospital.
Patients:
Consecutive nonintubated patients without mechanical ventilation, considered for volume expansion (VE).
Intervention:
We assessed hemodynamic status at baseline and after VE.
Measurements And Main Results:
We measured radial pulse pressure (PP) using an arterial catheter and peak velocity of femoral artery flow (VF) using continuous Doppler. Changes in PP and VF induced by a DIM (ΔPPdim and ΔVFdim) were calculated in 23 patients. ΔPPdim and ΔVFdim ≥12% predicted responders to VE with sensitivity of 90% and specificity of 100%.
Conclusions:
In a restricted population of SB patients with severe sepsis or acute pancreatitis, ΔPPdim and ΔVFdim are accurate indices for predicting fluid responsiveness. These results should be confirmed in a larger population before validating their use in current practice.
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