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Published on: February 6, 2019
[Fertility after prostate brachytherapy with Iode 125 permanent implants for localized prostate cancer]
B Delaunay1, M Delannes, J-M Bachaud
1Département d'urologie et d'andrologie, CHU Rangueil, 1, avenue J.-Poulhes, TSA 50032, 31059 Toulouse cedex 9, France.
Summary
Men treated with prostate brachytherapy showed semen quality that could lead to pregnancy, though contraception is advised post-treatment. This study highlights fertility preservation options for prostate cancer patients.
Area of Science:
- Reproductive medicine
- Oncology
- Urology
Context:
- Prostate cancer diagnosis is increasing in middle-aged men.
- Fertility preservation is a growing concern for these patients.
- Brachytherapy is a prostate cancer treatment that maintains ejaculation function.
Purpose:
- To evaluate the fertility of men treated with prostate brachytherapy.
- To provide better information for patients regarding fertility after treatment.
- To assess semen quality and pregnancy potential post-brachytherapy.
Summary:
- A study evaluated four sexually active men (ages 43-61) treated with iodine-125 prostate brachytherapy.
- Post-treatment semen analysis, over a year after brachytherapy, revealed spermatozoa with moderate asthenospermia and severe hypospermia.
- Despite semen abnormalities, the samples were consistent with potential for spontaneous pregnancy, with one case of miscarriage noted.
Impact:
- Findings inform patient counseling on fertility preservation options after prostate cancer treatment.
- Highlights the need for continued contraception post-brachytherapy if the partner is not menopausal.
- Contributes to understanding the reproductive health implications of brachytherapy for prostate cancer survivors.
