Jove
Visualize
Contact Us

Related Concept Videos

Genetic Variation01:25

Genetic Variation

Genetic variation is the diversity in DNA sequences found among individuals of the same species. This diversity is crucial for a species' survival because it helps organisms adapt to environmental changes. Genetic variation begins with fertilization, where an egg and sperm cell merge. Each of these cells carries 23 chromosomes, up to 46 in the fertilized egg. Chromosomes are long DNA strands that contain genes, the basic units of heredity.
Genes exist in different versions called alleles, which...
Frequency-dependent Selection01:21

Frequency-dependent Selection

When the fitness of a trait is influenced by how common it is (i.e., its frequency) relative to different traits within a population, this is referred to as frequency-dependent selection. Frequency-dependent selection may occur between species or within a single species. This type of selection can either be positive—with more common phenotypes having higher fitness—or negative, with rarer phenotypes conferring increased fitness.
Incomplete Dominance01:43

Incomplete Dominance

Gregor Mendel's work (1822 - 1884) was primarily focused on pea plants. Through his initial experiments, he determined that every gene in a diploid cell has two variants called alleles inherited from each parent. He suggested that amongst these two alleles, one allele is dominant in character and the other recessive. The combination of alleles determines the phenotype of a gene in an organism.
Human Genetics01:28

Human Genetics

Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
The complex relationship between genetics and psychology is observable through common biological components such...
Genetic Lingo01:11

Genetic Lingo

Overview
Principles of Pharmacogenetics: Types of Genetic Variants01:27

Principles of Pharmacogenetics: Types of Genetic Variants

The human genome is over 99.9% identical between individuals, yet genetic differences exist at millions of bases. The human genome contains approximately 3 million variant positions per individual, many of which are heterozygous, contributing to genetic diversity and individual traits. Genetic variations include single-nucleotide polymorphisms (SNPs), insertions, deletions, and copy number variations (CNVs).SNPs, the most common variation, involve single-base changes in DNA. These can be...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Investigating the evolutionary history of the biosynthetic gene cluster for the cytotoxic purine analog, 6-thioguanine.

Molecular genetics and genomics : MGG·2026
Same author

A semi-selective differential medium for identifying strains of Pantoea from environmental samples.

FEMS microbiology letters·2025
Same author

The expanding antimicrobial diversity of the genus Pantoea.

Microbiological research·2024
Same author

Distribution and comparative genomic analysis of antimicrobial gene clusters found in <i>Pantoea</i>.

Frontiers in microbiology·2024
Same author

Grazing preferences of three species of amoebae on cyanobacteria and green algae.

The Journal of eukaryotic microbiology·2024
Same author

A replica plating method for efficient, high-throughput screening of antibiotic gene clusters in bacteria uncovers a holomycin-like cluster in the clinical isolate, Pantoea agglomerans 20KB447973.

Journal of microbiological methods·2023
Same journal

Host membranes provide hidden gateways for 'accidental pathogens'.

Trends in microbiology·2026
Same journal

Structural inequalities in global antimicrobial resistance governance.

Trends in microbiology·2026
Same journal

Environmental microbes as modulators of plant volatile landscapes: Implications for plant-insect chemical communication.

Trends in microbiology·2026
Same journal

Beyond AMGs: Phage-encoded transcription and sigma factors as understudied virocell reprogramming tools.

Trends in microbiology·2026
Same journal

Cronobacter spp.

Trends in microbiology·2026
Same journal

Anaerobic lignin deconstruction: A game changer for lignocellulosic biorefineries.

Trends in microbiology·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: May 26, 2026

Genetic Mapping of Thermotolerance Differences Between Species of Saccharomyces Yeast via Genome-Wide Reciprocal Hemizygosity Analysis
10:08

Genetic Mapping of Thermotolerance Differences Between Species of Saccharomyces Yeast via Genome-Wide Reciprocal Hemizygosity Analysis

Published on: August 12, 2019

Host specificity determinants as a genetic continuum.

Morgan W B Kirzinger1, John Stavrinides

  • 1Department of Biology, University of Regina, 3737 Wascana Parkway, Regina, Saskatchewan, S4S 0A2, Canada.

Trends in Microbiology
|December 27, 2011
PubMed
Summary
This summary is machine-generated.

Microbial host specificity changes, especially in animal pathogens, can impact human health. Genetic modifications in microbes, from single residues to genomic islands, drive these host jumps.

More Related Videos

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations
08:03

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations

Published on: December 7, 2021

Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry
05:53

Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry

Published on: June 21, 2018

Related Experiment Videos

Last Updated: May 26, 2026

Genetic Mapping of Thermotolerance Differences Between Species of Saccharomyces Yeast via Genome-Wide Reciprocal Hemizygosity Analysis
10:08

Genetic Mapping of Thermotolerance Differences Between Species of Saccharomyces Yeast via Genome-Wide Reciprocal Hemizygosity Analysis

Published on: August 12, 2019

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations
08:03

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations

Published on: December 7, 2021

Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry
05:53

Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry

Published on: June 21, 2018

Area of Science:

  • Microbiology
  • Genetics
  • Evolutionary Biology

Background:

  • Host specificity is crucial for interactions between microbes and their hosts in clinical and agricultural settings.
  • Changes in host specificity of animal pathogens pose significant risks to human health.
  • Microbial genome studies reveal diverse genetic changes can alter host associations.

Purpose of the Study:

  • To review host specificity determinants across viruses, bacteria, and fungi.
  • To present these determinants within a genetic continuum.
  • To highlight the impact of genetic modifications on microbial host jumps.

Main Methods:

  • Literature review of genome-level studies.
  • Analysis of genetic modifications influencing host specificity.
  • Categorization of determinants along a genetic spectrum.

Main Results:

  • Host specificity is influenced by genetic changes ranging from single amino acid residues to entire genomic islands.
  • Diverse microbial pathogens (viruses, bacteria, fungi) exhibit such modifications.
  • These genetic alterations are key drivers of host switching events.

Conclusions:

  • Genetic modifications are fundamental to microbial host specificity and host jumps.
  • Understanding these genetic underpinnings is vital for predicting and managing pathogen emergence.
  • A continuum of genetic changes explains the evolution of host associations in microbes.