Related Experiment Video
Updated: May 26, 2026

High Frequency Ultrasound for the Analysis of Fetal and Placental Development In Vivo
Published on: November 8, 2018
The value of adding a universal booking scan to an existing protocol of routine mid-gestation ultrasound scan
Elizabeth J Poggenpoel1, Lutgart T G M Geerts, Gerhardus B Theron
1Department of Obstetrics and Gynaecology, Tygerberg Hospital, University of Stellenbosch, Tygerberg, South Africa. ejpoggenpoel@hotmail.com
Objective:
To compare 2 routine obstetric ultrasound protocols regarding number of clinically relevant events detected and total ultrasound workload.
Methods:
An interventional before-and-after study comparing 2 groups of 750 consecutive low-risk pregnant women was conducted. The 1st group was routinely offered mid-trimester ultrasound and selective ultrasound examinations for specific indications; the 2nd group was, in addition to this, offered a scan at 1st prenatal visit.
Results:
The groups were comparable at baseline, and 78% underwent booking scan. The expanded protocol showed no improvement in detection of most clinically relevant findings but did detect twins slightly earlier (P=0.3) and significantly reduced the number of presumed post-term deliveries (8.4% vs 13.1%; OR 0.61 [95% CI, 0.41-0.90]). Although more women were scanned at any point or <24 weeks (P<0.001), the increase in women receiving a properly timed fetal anomaly scan was small (60.7% vs 52.3%; P=0.003). Total ultrasound workload increased by 74%, mainly because of more follow-up scans (323 vs 122) and more women being scanned for the 1st time >24 weeks (146 vs 51; P<0.001).
Conclusion:
The results do not support a policy of routine booking scans and revealed no significant benefit apart from a small reduction in presumed post-term pregnancies.
Related Concept Videos
Ultrasound I: Abdominal Ultrasonography
Abdominal ultrasonography, commonly known as abdominal ultrasound, is a vital, non-invasive medical imaging technique widely used in healthcare.
Procedure:
This diagnostic tool allows the clinician to visually inspect internal structures within the abdomen, including vital organs such as the liver, gallbladder, pancreas, kidneys, and spleen.
The abdominal ultrasound process begins with applying a special gel to the patient's skin over the abdomen. This gel enhances the...
Imaging Studies II: Ultrasonography
Ultrasonography
During an ultrasonography procedure, a handheld device called a...
Ultrasound II: Endoscopic Ultrasound and FibroScan
Endoscopic Ultrasound (EUS):

