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Related Concept Videos

Probiotics01:22

Probiotics

Probiotics are live, non-pathogenic microorganisms that confer health benefits by modulating the gut microbiota. The human gastrointestinal tract harbors a complex microbial ecosystem, and the balance of this microbiota is crucial for digestive and systemic health. Among the most extensively studied and utilized probiotics are species formerly classified within the genera Lactobacillus and Bifidobacterium. These organisms not only naturally colonize the human gut but are also consumed through...
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy01:26

Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy

Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
Endoscopic Procedures II: Colonoscopy01:25

Endoscopic Procedures II: Colonoscopy

The colon, or large intestine, is the final segment of the digestive system. Its primary functions include absorbing water and vitamins produced by gut bacteria and transforming waste from liquid to solid to form stool. In adults, the large intestine is approximately 5 feet long and consists of four main sections:
Peptic Ulcer Disease V: Surgical Management and Nursing Care01:25

Peptic Ulcer Disease V: Surgical Management and Nursing Care

Surgical management and nursing care are crucial in treating Peptic Ulcer Disease (PUD). Here is an organized and enhanced overview of the surgical interventions and the associated nursing care for PUD:
Surgical Interventions for Peptic Ulcer Disease

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Related Experiment Video

Updated: May 26, 2026

Murine Ileocolic Bowel Resection with Primary Anastomosis
08:49

Murine Ileocolic Bowel Resection with Primary Anastomosis

Published on: October 29, 2014

Preoperative probiotics decrease postoperative infectious complications of colorectal cancer.

Ji-Wei Zhang1, Peng Du, Jun Gao

  • 1Department of Anorectal Surgery, Xin-Hua Hospital, Shanghai Jiaotong University, China. zjw1226863@yahoo.com.cn

The American Journal of the Medical Sciences
|December 27, 2011
PubMed
Summary

Preoperative probiotics significantly reduced postoperative infections in colorectal cancer patients by maintaining gut flora and boosting immunity. This intervention helps minimize complications following surgery.

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Evaluating Cell Death Using Cell-Free Supernatant of Probiotics in Three-Dimensional Spheroid Cultures of Colorectal Cancer Cells
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Evaluating Cell Death Using Cell-Free Supernatant of Probiotics in Three-Dimensional Spheroid Cultures of Colorectal Cancer Cells

Published on: June 13, 2020

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Last Updated: May 26, 2026

Murine Ileocolic Bowel Resection with Primary Anastomosis
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Evaluating Cell Death Using Cell-Free Supernatant of Probiotics in Three-Dimensional Spheroid Cultures of Colorectal Cancer Cells
06:07

Evaluating Cell Death Using Cell-Free Supernatant of Probiotics in Three-Dimensional Spheroid Cultures of Colorectal Cancer Cells

Published on: June 13, 2020

Area of Science:

  • Gastroenterology
  • Oncology
  • Microbiology

Background:

  • Colorectal cancer surgery poses risks of postoperative infections.
  • Maintaining gut microbiota balance is crucial for patient recovery.

Purpose of the Study:

  • To investigate the impact of oral bifid triple viable probiotics on patients undergoing colorectal cancer surgery.
  • To assess the effects on intestinal flora, gut barrier function, and immune response.

Main Methods:

  • Randomized controlled trial with 60 patients undergoing colorectal resection.
  • Preoperative administration of probiotics or placebo for 3 days.
  • Evaluation of fecal cultures, serum markers (endotoxins, D-lactic acid, immunoglobulins, IL-6, CRP), and infection rates.

Main Results:

  • Probiotics reversed the inversion of Bifidobacterium/Escherichia ratio postoperatively.
  • Reduced levels of endotoxins, D-lactic acid, IL-6, and C-reactive protein in the probiotic group.
  • Significantly lower incidence of postoperative infectious complications in the probiotic group (10.0% vs. 33.3%).

Conclusions:

  • Preoperative probiotics minimize postoperative infectious complications in colorectal cancer patients.
  • Mechanisms include maintaining intestinal flora and preventing bacterial translocation.
  • Probiotics enhance systemic/localized immunity and attenuate stress response.