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Related Experiment Video

Updated: May 26, 2026

Stereotactic Radiosurgery for Gynecologic Cancer

Stereotactic Radiosurgery for Gynecologic Cancer

Published on: April 17, 2012

Gamma knife radiosurgery for brainstem metastasis.

Tae Won Yoo¹, Eun Suk Park, Do Hoon Kwon

¹Department of Neurosurgery, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.

Journal of Korean Neurosurgical Society

|December 27, 2011

Summary

Gamma Knife Radiosurgery (GKRS) offers a safe and effective treatment for brainstem metastases, achieving an 87.5% local tumor control rate. Patient

Keywords:

Brainstem tumor Gamma knife radiosurgery Metastasis Stereotactic radiosurgery

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Modeling Brain Metastasis by Internal Carotid Artery Injection of Cancer Cells

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Area of Science:

Neurosurgery
Radiation Oncology
Oncology

Background:

Brainstem metastases are challenging to treat with conventional methods.
Gamma Knife Radiosurgery (GKRS) has emerged as a viable treatment option.

Purpose of the Study:

To evaluate the safety and efficacy of GKRS for brainstem metastases.
To identify prognostic factors influencing survival after GKRS.

Main Methods:

Retrospective analysis of 32 patients treated with GKRS for brainstem metastases (1992-2010).
Tumor locations included pons, midbrain, and medulla oblongata.
Follow-up via MRI, with survival analysis using Kaplan-Meier method.

Main Results:

87.5% local tumor control rate observed.
Mean progression-free survival of 12.2 months.
Favorable prognostic factors included Karnofsky performance status >70 and Recursive Partitioning Analysis class 1 or 2.

Conclusions:

GKRS is a safe and effective treatment for brainstem metastases.
Patient's clinical status is crucial for determining survival outcomes.