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Osteosarcoma of the patella: a case report
Shuichi Chida1, Hiroyuki Nagasawa, Kyoji Okada
1Department of Orthopedic Surgery, Akita University Graduate School of Medicine, 1-1-1 Hondo, Akita, 010-8543, Japan. cshuichi@doc.med.akita-u.ac.jp
Upsala Journal of Medical Sciences
|December 28, 2011
Summary
This study details a rare case of conventional osteosarcoma in the patella of a 30-year-old woman. Despite treatment, the patient developed pathological fractures and spinal metastases, highlighting the aggressive nature of this rare bone cancer.
Area of Science:
- Orthopedic Oncology
- Skeletal Radiology
- Tumor Histopathology
Background:
- Osteosarcoma is a primary malignant bone tumor, typically affecting long bones, with rare occurrences in the patella.
- Patellar osteosarcoma presents diagnostic challenges due to its rarity and potential for mimicking benign conditions.
Observation:
- A 30-year-old Japanese woman presented with a 2-year history of knee pain, exhibiting patellar enlargement with mixed osteolytic and sclerotic lesions.
- Imaging revealed soft tissue extension, and biopsy confirmed conventional osteosarcoma with abundant osteoid production by malignant spindle cells.
Findings:
- The patient showed no response to neoadjuvant chemotherapy and sustained a pathological fracture during treatment.
- An above-the-knee amputation was performed, followed by adjuvant chemotherapy, but multiple thoracic vertebral metastases developed 20 months post-surgery.
Implications:
- This case underscores the aggressive behavior and poor prognosis associated with rare patellar osteosarcoma.
- It highlights the importance of thorough diagnostic evaluation for persistent knee pain and the challenges in managing advanced-stage patellar osteosarcoma.
