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Updated: May 26, 2026

Live Cell Imaging of Chromosome Segregation During Mitosis
Published on: March 14, 2018
Bacterial chromosome segregation
Christophe Possoz1, Ivan Junier, Olivier Espeli
1Centre de Genetique Moleculaire, CGM-CNRS-UPR3404, Avenue de la terrasse, 91198 Gif sur Yvette, France.
Abstract:
Dividing cells have mechanisms to ensure that their genomes are faithfully segregated into daughter cells. In bacteria, the description of these mechanisms has been considerably improved in the recent years. This review focuses on the different aspects of bacterial chromosome segregation that can be understood thanks to the studies performed with model organisms: Escherichia coli, Bacillus subtilis, Caulobacter crescentus and Vibrio cholerae. We describe the global positionning of the nucleoid in the cell and the specific localization and dynamics of different chromosomal loci, kinetic and biophysic aspects of chromosome segregation are presented. Finally, a presentation of the key proteins involved in the chromosome segregation is made.
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