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Updated: May 26, 2026

A High Throughput MHC II Binding Assay for Quantitative Analysis of Peptide Epitopes
Published on: March 25, 2014
Immunoinformatics: how in silico methods are re-shaping the investigation of peptide immune specificity
Lawrence Jin Kiat Wee1, Shen Jean Lim, Lisa F P Ng
1Singapore Immunology Network, 8A Biomedical Grove, No. 04-06 Immunos, Biopolis, Singapore 138648. victor@bic.nus.edu.sg
Abstract:
In the past decade, information technology has enabled synergistic advances in key domains of immunological research including the development of diagnostics and vaccines. Computational methods of epitope mapping now play instrumental roles in bench experiments, by facilitating the selection of immunogenic targets and the modeling of downstream cellular responses. In this article, we summarize the latest development and application of immune epitope prediction methods and discuss future directions in this field which could enhance our understanding of immune specificity.
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