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TMT Sample Preparation for Proteomics Facility Submission and Subsequent Data Analysis
Published on: June 8, 2020
Pediatric proteomics: an introduction
Jeanne Young1, William L Stone
1Department of Pediatrics, James H. Quillen College of Medicine, East Tennessee State University, Johnson City, TN 37604, USA.
Frontiers in Bioscience (Scholar Edition)
|December 29, 2011
Summary
Proteomics, the study of proteins, is revolutionizing pediatric medicine. This review explores its role in personalized care and overcoming challenges for clinical application.
Area of Science:
- Biochemistry
- Pediatric Medicine
- Systems Biology
Background:
- Proteomics offers a global view of proteins within biological systems.
- It complements other 'omics' fields in systems biology.
- Understanding protein expression is crucial for advancing medical research.
Purpose of the Study:
- To introduce the paradigm shift proteomics brings to pediatric medicine and research.
- To provide an overview of proteomics, its technologies, and methodologies.
- To discuss the potential of proteomics in personalized pediatric medicine.
Main Methods:
- Overview of proteomics principles and technologies.
- Discussion of systems biology context.
- Identification of challenges and opportunities in pediatric proteomics.
Main Results:
- Proteomics provides a comprehensive analysis of the proteome.
- Key technologies and methodologies are being developed.
- Obstacles to clinical implementation in pediatrics are being identified.
Conclusions:
- Proteomics holds significant potential for personalized pediatric medicine.
- Further technological and methodological advancements are needed for optimal clinical utility.
- This review serves as a foundation for understanding proteomics in pediatrics.
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