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Published on: August 10, 2011
The infancy-childhood growth spurt
1Department of Anatomy, University of Gothenburg, Sweden.
Insights
The infancy-childhood growth spurt (IC spurt) begins between 6-12 months, marking a key period for growth regulation. A delayed IC spurt negatively impacts final height, especially in children with growth disorders or GH deficiency.
Area of Science:
- Pediatrics
- Human Growth and Development
- Endocrinology
Background:
- Early human linear growth exhibits instability with a notable increase in rate between 6 and 12 months.
- This period signifies the onset of the infancy-childhood growth spurt (IC spurt), aligning with the childhood phase of the infancy-childhood-puberty growth model.
Purpose of the Study:
- To define the onset and completion of the infancy-childhood growth spurt (IC spurt).
- To investigate the role of growth hormone (GH) in regulating early growth.
- To examine the impact of a delayed IC spurt on attained height.
Main Methods:
- Analysis of normal human linear growth patterns.
- Correlation of IC spurt onset with the infancy-childhood-puberty growth model.
- Observation of growth patterns in children with growth disorders and GH deficiency.
Main Results:
- The infancy-childhood growth spurt (IC spurt) begins between 6-12 months and concludes around 3 years of age.
- Growth hormone (GH) appears to significantly regulate growth starting at the onset of the IC spurt.
- Delayed IC spurt is prevalent in children with growth disorders (30-50%) and those in deprived environments, leading to reduced attained height.
Conclusions:
- The infancy-childhood growth spurt (IC spurt) is a critical phase in early development, influenced by growth hormone (GH).
- Delayed onset of the IC spurt has detrimental effects on final height, highlighting the importance of timely growth regulation.
Abstract:
Early normal human linear growth is unstable and oscillates owing to an increase in growth rate between 6 and 12 months of age. This defines the onset of the infancy-childhood growth spurt (IC spurt). The onset is identical with the onset of the childhood component of the infancy-childhood-puberty growth model. The IC spurt is completed when the infancy component of this model has virtually ceased, at around 3 years of age. Additional observations suggest that its onset represents the age at which growth hormone (GH) begins to regulate growth significantly. The negative impact of late onset of the IC spurt on attained height is illustrated and discussed. A delayed spurt is observed in 30-50% of children with growth-related disorders and of infants living in a poor area of a developing country. The IC spurt is absent in children with GH deficiency who receive no hormonal therapy.
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