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Related Experiment Video

Updated: May 26, 2026

Optimization of a Multiplex RNA-based Expression Assay Using Breast Cancer Archival Material
11:12

Optimization of a Multiplex RNA-based Expression Assay Using Breast Cancer Archival Material

Published on: August 1, 2018

[Modern pathologic diagnostics in breast cancer].

János Szoke1, Nóra Udvarhelyi

  • 1Országos Onkológai Intézet Sebészi és Molekuláris Daganatpatológiai Centrum Budapest Ráth Gy. u. 7-9. 1122. szoke.j@oncol.hu

Orvosi Hetilap
|December 30, 2011
PubMed
Summary

This review covers key pathological and molecular features of invasive breast cancer. Understanding these aspects is crucial for accurate diagnosis and effective treatment strategies.

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Pathological Diagnosis, Work-Up and Reporting of Breast Cancer 1st Central-Eastern European Professional Consensus Statement on Breast Cancer.

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Area of Science:

  • Oncology
  • Pathology
  • Genomics

Context:

  • Breast cancer diagnosis relies on morphological assessment.
  • Standard pathological parameters include tumor size, lymph node status, and histological grade.
  • Estrogen receptor, progesterone receptor, and HER2 status are routinely evaluated.

Purpose:

  • To review prognostically significant aspects of diagnostic pathology for invasive breast cancer.
  • To discuss the molecular classification of invasive breast cancer.
  • To highlight the role of molecular techniques in understanding breast cancer.

Summary:

  • Morphological and molecular features are essential for breast cancer diagnosis and prognosis.
  • Pathological parameters guide clinical treatment decisions.
  • Gene-expression profiling and molecular tests offer further prognostic information.

Impact:

  • Improved understanding of breast cancer heterogeneity.
  • Enhanced prognostic accuracy for patient care.
  • Foundation for developing targeted therapies and personalized medicine.

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