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Updated: May 26, 2026

Use of Interferon-γ Enzyme-linked Immunospot Assay to Characterize Novel T-cell Epitopes of Human Papillomavirus
Published on: March 8, 2012
[Analysis on human papillomavirus 16 and 18 types infection among 805 patients with common anorectal lesions]
Jian-xiang Geng1, Zhi-ming Fan, Yi-jiang Ding
1Department of Pathology, The Third Affiliated Hospital, Nanjing Traditional Chinese Medical University, Nanjing 210001, China. wxf_1982@163.com
Objective:
To analyze the infection condition of human papillomavirus (HPV) type 16 and 18 in the squamous cells and columnar cells of patients with common anorecatal lesions.
Methods:
Infections of HPV type 16 and 18 were determined with real-time fluorescent quantitative PCR in the wax-embedded surgical specimen of 805 patients with common anorectal diseases.
Results:
The overall infection rate among 805 patients with anorecatal lesions was 66.1% (532/805). The infection rate was 82.6% (95/115) in patients with mixed hemorrhoids, 76.5% (88/115) in anal papillary fibromas, 74.8% (86/115) in internal hemorrhoids, 72.2% (83/115) in fistulas, 69.6% (80/115) in external hemorrhoids, 47.8% (55/115) in anal perianal abscesses, and 39.1% (45/115) in anal fissures.
Conclusion:
Infection rate of HPV type 16, 18 in common anorectal lesions is high.
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