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Updated: May 26, 2026

An Integrated System to Remotely Trigger Intracellular Signal Transduction by Upconversion Nanoparticle-mediated Kinase Photoactivation
Published on: August 30, 2017
Nucleic acid templated uncaging of fluorophores using Ru-catalyzed photoreduction with visible light
Manuel Röthlingshöfer1, Katarzyna Gorska, Nicolas Winssinger
1Institut de Science et Ingénierie Supramoléculaires (ISIS - UMR 7006), Université de Strasbourg - CNRS, 8 allée Gaspard Monge, F67000 Strasbourg, France.
Abstract:
Hybridization-based reactions have attracted significant attention. The nucleic acid templated photocatalyzed azide reduction using catalytic amounts of a [Ru(bpy)(2)phen](2+) conjugate is reported. The reaction could be performed with as little as 2% of the Ru nucleic acid probe and was shown to productively unquench 7-azido-coumarin as well as uncage a small molecule.
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