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Heterocycle synthesis via direct C-H/N-H coupling

Enrico T Nadres1, Olafs Daugulis

  • 1Department of Chemistry, University of Houston, Houston, Texas 77204-5003, USA.

Journal of the American Chemical Society
|December 31, 2011
PubMed
Summary

A novel palladium-catalyzed coupling method efficiently forms five- and six-membered heterocycles. This versatile cyclization works for various C-H bonds, including sp2, aliphatic, and benzylic sp3 types.

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