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Related Concept Videos

Imaging Studies for Cardiovascular System V: CT01:28

Imaging Studies for Cardiovascular System V: CT

Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT01:25

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
Cardiac Catheterization I: Pre-Procedure Overview01:28

Cardiac Catheterization I: Pre-Procedure Overview

Cardiac catheterization is an invasive diagnostic technique used to identify and evaluate structural and functional diseases of the heart and major blood vessels. This technique diagnoses congenital heart disease, coronary artery disease, valvular heart disease, and coronary spasms and assesses ventricular function. It helps guide treatment decisions, including the need for revascularization procedures like percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) and...
Imaging Studies for Cardiovascular System IV: CMRI01:21

Imaging Studies for Cardiovascular System IV: CMRI

Cardiovascular magnetic resonance imaging, or CMRI, is a non-invasive diagnostic test that employs a magnetic field and radiofrequency waves to create precise images of the heart and arteries. It provides comprehensive information about cardiac anatomy, function, perfusion, and tissue characterization without ionizing radiation.IndicationsCMRI diagnoses various heart conditions, including tissue damage from heart attacks, ischemic heart disease, myocarditis, aortic issues (tears, aneurysms,...
Imaging Studies for Cardiovascular System I:Echocardiography01:17

Imaging Studies for Cardiovascular System I:Echocardiography

Cardiac imaging studies encompass a wide range of noninvasive and minimally invasive techniques designed to visualize the heart's structure and function in detail. One such technique is echocardiography, which uses high-frequency ultrasound waves to produce detailed images of the heart, known as echocardiograms.
Indications: Echocardiography is utilized to diagnose heart failure, valve disorders, and myocardial infarction. It also assesses cardiac structures' size, shape, and motion, evaluates...

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High-Resolution Cardiac Positron Emission Tomography/Computed Tomography for Small Animals
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High-Resolution Cardiac Positron Emission Tomography/Computed Tomography for Small Animals

Published on: December 16, 2022

Infarct detection with a comprehensive cardiac CT protocol.

Brian B Ghoshhajra1, Pal Maurovich-Horvat, Tust Techasith

  • 1Cardiac MR PET CT Program, Department of Radiology and Division of Cardiology, Massachusetts General Hospital and Harvard Medical School, 165 Cambridge Street, Suite 400, Boston, MA 02114, USA.

Journal of Cardiovascular Computed Tomography
|January 3, 2012
PubMed
Summary
This summary is machine-generated.

Cardiac CT accurately detects myocardial infarction (MI) using a combination of techniques. A comprehensive approach including regional wall motion abnormalities (RWMA), rest perfusion defects (RPD), and delayed contrast enhancement (DCE) offers the highest diagnostic accuracy.

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Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques
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Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques

Published on: June 11, 2019

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Last Updated: May 26, 2026

High-Resolution Cardiac Positron Emission Tomography/Computed Tomography for Small Animals
11:09

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Published on: December 16, 2022

Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques
06:29

Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques

Published on: June 11, 2019

Area of Science:

  • Cardiovascular Imaging
  • Radiology
  • Medical Diagnostics

Background:

  • Cardiac CT offers potential for comprehensive myocardial infarction (MI) detection through regional wall motion abnormalities (RWMA), rest perfusion defects (RPD), and delayed contrast enhancement (DCE).
  • The diagnostic accuracy of these cardiac CT techniques for MI detection remains largely unknown.

Purpose of the Study:

  • To evaluate the diagnostic accuracy of individual and combined cardiac CT techniques for myocardial infarction (MI) detection.
  • To compare the accuracy of RWMA, RPD, and DCE assessed by cardiac CT against the universal definition of MI.

Main Methods:

  • A prospective study enrolled 48 patients with suspected coronary artery disease for a 64-detector row dual-source cardiac CT protocol.
  • The protocol included cine for RWMA, first-pass for RPD, and delayed imaging for DCE, with blinded reader assessment.
  • The 2007 American Heart Association universal definition of MI served as the gold standard.

Main Results:

  • Fifty percent of patients (24/48) were diagnosed with MI based on the universal definition.
  • Combined CT analysis achieved 90% accuracy, with 88% sensitivity and 92% specificity for per-patient MI detection.
  • Individual techniques showed lower accuracy: RWMA (79%), RPD (67%), and DCE (79%). A combination of DCE and cine demonstrated 85% accuracy and 92% sensitivity.

Conclusions:

  • Cardiac CT is a feasible method for infarct detection with good diagnostic accuracy when compared to the universal definition of MI.
  • A combined evaluation incorporating cine, RPD, and DCE provides the highest diagnostic accuracy for MI detection.
  • These findings support the integration of multiple CT techniques in future protocols for optimal MI detection.