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Updated: May 26, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
Feasibility of conservative medical treatment for pyoderma gangrenosum
Paolo Fioramonti1, Maria Giuseppina Onesti, Pasquale Fino
1Department of Dermatology and Plastic, Reconstructive and Aesthetic Surgery, University of Rome La Sapienza, Policlinico Umberto I, Viale Pantelleria, 35, Scala B, Interno 1/A, 00141, Rome, Italy.
Abstract:
Pyoderma gangrenosum (PG) is a chronic skin disease with an incidence of 3-10 per million, and it is often associated with underlying systemic disease. A case of PG of the left leg successfully treated with local debridement and advanced and compression dressings, without systemic treatment is reported. Progression and healing of the ulcer was incredibly rapid. The treatment of PG usually consists of systemic administration of corticosteroids. But wherever the administration of systemic immunosuppressive therapy is impractical, a topical treatment can be used. This type of treatment does not represent a mere palliative, but could be significant for healing, as in the case of our patient.
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