Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Cardiomyopathy I: Introduction and Classification

Cardiomyopathy I: Introduction and Classification

Cardiomyopathy, or CMP, is a group of diseases affecting the myocardial structure, impairing its ability to pump blood effectively. This condition can lead to arrhythmias, heart failure, or sudden cardiac death.Cardiomyopathies are classified into primary and secondary categories:Primary Cardiomyopathy refers to conditions involving only the heart muscle that are often idiopathic (of unknown cause) or genetic. They primarily affect the myocardium without the involvement of other systemic...

Cardiomyopathy III: Hypertrophic Cardiomyopathy

Cardiomyopathy III: Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...

Cardiomyopathy IV: Restrictive Cardiomyopathy

Cardiomyopathy IV: Restrictive Cardiomyopathy

Restrictive cardiomyopathy (RCM) is a rare heart muscle disease characterized by impaired ventricular filling due to stiffened ventricular walls, leading to significant diastolic dysfunction.EtiologyRestrictive cardiomyopathy can arise from both inherited and acquired diseases, many of which are systemic. It is categorized into four main types: infiltrative, storage, non-infiltrative, and endomyocardial diseases.Infiltrative diseases, such as amyloidosis, lead to RCM by depositing amyloid...

Cardiomyopathy II: Dilated Cardiomyopathy

Cardiomyopathy II: Dilated Cardiomyopathy

Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...

Cardiomyopathy V: Interprofessional Care

Cardiomyopathy V: Interprofessional Care

Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...

Imbalances in Cardiac Output

Imbalances in Cardiac Output

The heart's primary function is to pump blood throughout the body, maintaining a balance between blood sent out (cardiac output) and blood returning (venous return). If this balance is disrupted, it can result in congestive heart failure (CHF), a severe condition where the heart becomes an inefficient pump, leading to inadequate blood circulation.
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send blood...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Overview and potential role of omega-3 in COVID-19.

La Clinica terapeutica·2024

Same author

Development of a standardized methodology for transfer learning with QSAR models: a purely data-driven approach for source task selection.

SAR and QSAR in environmental research·2024

Same author

Prevalence of 25(OH)D insufficiency and overweight/obesity in an adult population from the Central Italy.

La Clinica terapeutica·2022

Same author

Predictors of intubation in COVID-19 patients treated with out-of-ICU continuous positive airway pressure.

Pulmonology·2021

Same author

[The use of RCGO triggers in the obstetric - gynecological procedures: the impact on the reduction of adeverse events. The experience of the Lombardia Region].

Igiene e sanita pubblica·2020

Same author

Cell-based multi-target QSAR model for design of virtual versatile inhibitors of liver cancer cell lines.

SAR and QSAR in environmental research·2020

Same journal

Identification of circRNA-mediated competing endogenous RNA network in the development of bladder urothelial carcinoma.

Journal of biological regulators and homeostatic agents·2021

Same journal

Dimethyl fumarate attenuates lipopolysaccharide-induced acute lung injury by inhibiting inflammation and oxidative stress.

Journal of biological regulators and homeostatic agents·2021

Same journal

Expression of NLR and IL-1β and their predictive efficacy value in acute myocardial infarction patients treated with aspirin combined with clopidogrel.

Journal of biological regulators and homeostatic agents·2021

Same journal

CircRNA (circ_0008057) promotes uremic serum-mediated proliferation and migration of vascular smooth muscle cells via miR-370/PLk1 signaling pathway.

Journal of biological regulators and homeostatic agents·2021

Same journal

Overexpression of miR-150-5p alleviates lipopolysaccharide-induced A549 cell injury in type II alveolar epithelial cells by inhibiting the FSTL1 signaling pathway.

Journal of biological regulators and homeostatic agents·2021

Same journal

Efficacy of early oral and perioral physiotherapy on feeding autonomy in preterm infants: results of randomized controlled trials.

Journal of biological regulators and homeostatic agents·2021

See all related articles

Search research articles

Related Experiment Video

Updated: May 26, 2026

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography

Published on: February 16, 2016

Left ventricular noncompaction cardiomyopathy.

G Riccioni¹, G A Prencipe, V Bucciarelli

¹Cardiology Unit, San Camillo De Lellis Hospital, Manfredonia, Foggia, Italy. griccioni@hotmail.com

Journal of Biological Regulators and Homeostatic Agents

|January 6, 2012

Summary

This summary is machine-generated.

Isolated left ventricular noncompaction (ILVNC) is a rare congenital heart defect. This case report highlights its diagnosis and varied clinical manifestations in a 58-year-old male patient.

More Related Videos

Dual-Dye Optical Mapping of Hearts from RyR2R2474S Knock-In Mice of Catecholaminergic Polymorphic Ventricular Tachycardia

Dual-Dye Optical Mapping of Hearts from RyR2^R2474S Knock-In Mice of Catecholaminergic Polymorphic Ventricular Tachycardia

Published on: December 22, 2023

Tachycardia-Induced Cardiomyopathy As a Chronic Heart Failure Model in Swine

Tachycardia-Induced Cardiomyopathy As a Chronic Heart Failure Model in Swine

Published on: February 17, 2018

Related Experiment Videos

Last Updated: May 26, 2026

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography

Published on: February 16, 2016

Dual-Dye Optical Mapping of Hearts from RyR2R2474S Knock-In Mice of Catecholaminergic Polymorphic Ventricular Tachycardia

Dual-Dye Optical Mapping of Hearts from RyR2^R2474S Knock-In Mice of Catecholaminergic Polymorphic Ventricular Tachycardia

Published on: December 22, 2023

Tachycardia-Induced Cardiomyopathy As a Chronic Heart Failure Model in Swine

Tachycardia-Induced Cardiomyopathy As a Chronic Heart Failure Model in Swine

Published on: February 17, 2018

Area of Science:

Cardiology
Developmental Biology
Medical Imaging

Background:

Isolated left ventricular noncompaction (ILVNC) is a rare congenital cardiac abnormality.
It arises from an amorphogenetic defect during embryonic development.
Diagnosis relies on characteristic imaging findings of prominent trabeculations and deep inter-trabecular spaces.

Observation:

The case involves a 58-year-old male patient.
The patient presented with clinical manifestations consistent with ILVNC.

Findings:

ILVNC presents with a spectrum of clinical issues.
These include ventricular arrhythmias, congestive heart failure, and cardio-embolic events like stroke.
Reduced global ventricular systolic function and valve incompetence are also observed.

Implications:

Early diagnosis of ILVNC is crucial for managing potential complications.
Understanding the embryogenesis of ILVNC aids in predicting clinical outcomes.
This case underscores the importance of recognizing ILVNC in adult patients presenting with cardiac symptoms.