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Updated: May 26, 2026

Extraction and Analysis of Taiwanese Green Propolis
Published on: January 7, 2019
Is propolis safe as an alternative medicine?
Maria Graça Miguel1, Maria Dulce Antunes
1Faculty of Sciences and Technology, Department of Chemistry and Pharmacy, University of Algarve, IBB, Center for Plant Biotechnology, Building 8, Campus de Gambelas, 8005-139 Faro, Portugal.
Propolis, a bee-produced resin, offers therapeutic benefits and is increasingly used in medicines and cosmetics. Its variable chemical composition necessitates standardization for quality control in complementary medicine.
Area of Science:
- Natural Products Chemistry
- Pharmacology
- Apitherapy
Background:
- Propolis is a resinous substance from honeybees, historically used for its therapeutic properties.
- It is globally produced, with composition varying based on local flora.
- Propolis is gaining importance in modern therapeutics, medicines, cosmetics, and homeopathic products.
Purpose of the Study:
- To review the phenolic and volatile fractions of propolis.
- To examine the biological properties of propolis.
- To highlight the need for standardization and quality control of propolis.
Main Methods:
- Literature review focusing on phenolic and volatile compounds.
- Analysis of reported biological activities.
- Evaluation of existing standardization efforts.
Main Results:
- Propolis composition is influenced by geographical origin and surrounding flora.
- Key therapeutic properties are linked to its phenolic and volatile constituents.
- Quality control and standardization are crucial for consistent efficacy.
Conclusions:
- Standardization, particularly for poplar-type propolis, is essential for its use in complementary and alternative medicine.
- Internationally accepted quality control measures are needed.
- Further research into propolis composition and biological activities will support its therapeutic applications.
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