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Updated: May 26, 2026
19:58
Palladium N-Heterocyclic Carbene Complexes: Synthesis from Benzimidazolium Salts and Catalytic Activity in Carbon-carbon Bond-forming Reactions
Published on: July 30, 2017
2-Chloro-N-(4-methyl-phen-yl)benzamide.
Acta Crystallographica. Section E, Structure Reports Online
|January 6, 2012
Summary
This study details the crystal structure of a chloro-substituted benzanilide derivative. Molecular analysis reveals specific orientations and intermolecular hydrogen bonding, forming chain-like structures in the solid state.
Area of Science:
- Organic Chemistry
- Crystallography
- Solid-State Chemistry
Background:
- Benzanilide derivatives are important scaffolds in medicinal chemistry.
- Understanding molecular packing and intermolecular interactions is crucial for material properties.
Purpose of the Study:
- To characterize the crystal structure of a novel ortho-chloro substituted benzanilide.
- To investigate the molecular geometry and intermolecular interactions in the solid state.
Main Methods:
- Single-crystal X-ray diffraction was employed to determine the molecular structure.
- Analysis of bond lengths, bond angles, and torsion angles provided geometric insights.
- Intermolecular interactions, specifically hydrogen bonding, were identified and analyzed.
Main Results:
- The crystal structure of C(14)H(12)ClNO was elucidated.
- An ortho-chlorine atom on the benzoyl ring was observed syn to the carbonyl group.
- A significant dihedral angle of 82.8° was found between the benzoyl and aniline rings.
- Infinite chains were formed via intermolecular N-H⋯O hydrogen bonds along the c-axis.
Conclusions:
- The study provides a detailed structural description of the title compound.
- The observed molecular conformation and hydrogen bonding pattern influence the crystal packing.
- This structural information can be valuable for designing related compounds with specific solid-state properties.
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