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High-Speed Atomic Force Microscopy Imaging of DNA Three-Point-Star Motif Self Assembly Using Photothermal Off-Resonance Tapping
Published on: March 22, 2024
Observation of backbone self-crossings of organismal DNAs through atomic force microscopy
Dawei Li1, Zhaoqi Yang, Bei Lv
1Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore.
Bioorganic & Medicinal Chemistry Letters
|January 7, 2012
Abstract:
It is demonstrated in our studies that intrinsic curvatures of organismal DNAs could lead to the generation of duplex backbone self-crossings in their relaxed forms. In addition, the backbone self-crossings of the organismal DNAs could be readily confirmed through atomic force microscopic examination.
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