Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

1.6K
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
1.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Pachy-reticular pseudodrusen associated with pachyvitelliform maculopathy.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie·2026
Same author

Vascular remodeling of macular neovascularization following switch to intravitreal faricimab in neovascular AMD.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie·2026
Same author

Centenarian patients with neovascular age-related macular degeneration.

Retina (Philadelphia, Pa.)·2026
Same author

SD-OCT AND OCTA: Distinct or Additional Information on Neovascular Activity? The COCTAEYL Study.

Retina (Philadelphia, Pa.)·2026
Same author

Intravitreal Tamponade Agents in Vitreoretinal Surgery: Current Advances and Future Directions.

Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde·2026
Same author

Lacquer Cracks Detection and Measurement Using Black-on-White Infrared Reflectance and Late-Phase Indocyanine Green Angiography in Pathologic Myopia.

Ophthalmology science·2025
Same journal

Dual-Hit Myopia Mechanism Unveiled by Multi-Omics: Opn1mw Deficiency Primed the Retina for Exaggerated Response to Environmental Defocus.

Investigative ophthalmology & visual science·2026
Same journal

Psychometric Performance of Children With Amblyopia During a Tablet-Based Adaptive Visual Acuity Assessment.

Investigative ophthalmology & visual science·2026
Same journal

The Molecular Basis of Ocular Aging: Mechanisms, Pathologies, and Emerging Therapeutics.

Investigative ophthalmology & visual science·2026
Same journal

Sensory Eye Dominance Remains Stable Across Binocular Combination and Rivalry in Normal and Anisometropic Amblyopic Vision.

Investigative ophthalmology & visual science·2026
Same journal

Exosome-Associated Gene Network and the Role of SPP1 in Herpes Stromal Keratitis and the Therapeutic Modulation by Ursolic Acid.

Investigative ophthalmology & visual science·2026
Same journal

Nonlinear Associations of Estimated Glucose Disposal Rate With Incident Age-Related Eye Diseases: Implications for Metabolic Risk Stratification.

Investigative ophthalmology & visual science·2026
See all related articles

Related Experiment Video

Updated: Mar 22, 2026

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
10:14

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Published on: May 26, 2023

4.4K

Choroidal changes associated with reticular pseudodrusen.

Giuseppe Querques1, Lea Querques, Raimondo Forte

  • 1Department of Ophthalmology, Centre Hospitalier Intercommunal de Creteil, University Paris Est Creteil, Creteil, France. giuseppe.querques@hotmail.it

Investigative Ophthalmology & Visual Science
|January 7, 2012
PubMed
Summary
This summary is machine-generated.

Reticular pseudodrusen is associated with a thinner choroid, as visualized by indocyanine green angiography (ICGA) and enhanced depth imaging optical coherence tomography (EDI OCT). These findings highlight choroidal changes in reticular pseudodrusen, impacting retinal health.

More Related Videos

Application of Optical Coherence Tomography to a Mouse Model of Retinopathy
08:22

Application of Optical Coherence Tomography to a Mouse Model of Retinopathy

Published on: January 12, 2022

5.5K
Culturing of Retinal Pigment Epithelial Cells on an Ex Vivo Model of Aged Human Bruch's Membrane
08:32

Culturing of Retinal Pigment Epithelial Cells on an Ex Vivo Model of Aged Human Bruch's Membrane

Published on: April 12, 2018

10.8K

Related Experiment Videos

Last Updated: Mar 22, 2026

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
10:14

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Published on: May 26, 2023

4.4K
Application of Optical Coherence Tomography to a Mouse Model of Retinopathy
08:22

Application of Optical Coherence Tomography to a Mouse Model of Retinopathy

Published on: January 12, 2022

5.5K
Culturing of Retinal Pigment Epithelial Cells on an Ex Vivo Model of Aged Human Bruch's Membrane
08:32

Culturing of Retinal Pigment Epithelial Cells on an Ex Vivo Model of Aged Human Bruch's Membrane

Published on: April 12, 2018

10.8K

Area of Science:

  • Ophthalmology
  • Medical Imaging
  • Retinal Diseases

Background:

  • Reticular pseudodrusen are associated with age-related macular degeneration (AMD).
  • Understanding choroidal morphology is crucial for diagnosing and managing retinal conditions.

Purpose of the Study:

  • To analyze choroidal changes in patients with reticular pseudodrusen using indocyanine green angiography (ICGA) and enhanced depth imaging spectral-domain optical coherence tomography (EDI SD-OCT).

Main Methods:

  • ICGA and EDI SD-OCT were performed on 22 patients with reticular pseudodrusen.
  • A control group of 21 patients with early AMD (without pseudodrusen) underwent EDI OCT.

Main Results:

  • Reticular patterns appeared as hypofluorescent lesions on ICGA, adjacent to but not overlying large choroidal vessels.
  • The mean subfoveal choroidal thickness was significantly reduced in the reticular pseudodrusen group (174.6 ± 10.1 μm) compared to controls (241.4 ± 16.5 μm).
  • Choroidal thickness was generally thinner in eyes with reticular pseudodrusen, except for a localized thickening superior to the fovea.

Conclusions:

  • Reticular patterns in reticular pseudodrusen are hypofluorescent on ICGA.
  • EDI SD-OCT revealed an overall thinned choroid in eyes with reticular pseudodrusen.