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The effect of ageing on autonomic nervous system function.
T J Ingall1, J G McLeod, P C O'Brien
1Department of Medicine, University of Sydney, NSW.
Australian and New Zealand Journal of Medicine
|August 1, 1990
Summary
Autonomic nervous system function tests show age-related changes, particularly in vagal function. Sympathetic function remains stable with age, highlighting the need for age-specific reference values in autonomic testing.
Area of Science:
- Physiology
- Autonomic Nervous System Research
Background:
- The autonomic nervous system regulates involuntary bodily functions.
- Age can influence physiological processes, including autonomic control.
Purpose of the Study:
- To investigate the impact of aging on autonomic nervous system function.
- To differentiate age-related effects on vagal versus sympathetic cardiovascular function.
Main Methods:
- Utilized a battery of invasive and non-invasive tests.
- Assessed autonomic function in 76 healthy individuals across a wide age range (5-85 years).
Main Results:
- Significant age-related effects were observed in tests of vagal cardiovascular function.
- No significant age-related effects were detected in tests of sympathetic cardiovascular function.
Conclusions:
- Age is a critical factor when interpreting autonomic function tests, especially those assessing vagal tone.
- Laboratories should establish distinct, age-specific control values for accurate autonomic function assessment.