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Related Experiment Video

Updated: May 26, 2026

In vivo Evaluation of Mucociliary Clearance in Mice

In vivo Evaluation of Mucociliary Clearance in Mice

Published on: December 18, 2020

Cilia in vertebrate development and disease.

Edwin C Oh¹, Nicholas Katsanis

¹Center for Human Disease Modeling, Department of Cell Biology, Duke University, Durham NC 27710, USA. Edwin.oh@duke.edu

Development (Cambridge, England)

|January 7, 2012

Summary

The vertebrate cilium, an ancient organelle, is vital for cell signaling and sensory perception. Its structure, function, and associated diseases are now better understood.

Area of Science:

Cell Biology
Genetics
Developmental Biology

Background:

The vertebrate cilium is an ancient organelle with increasingly recognized roles.
It is crucial for signaling and sensory perception in development and homeostasis.

Purpose of the Study:

To provide an overview of vertebrate cilium structure, function, and distribution.
To highlight pathologies linked to cilium dysfunction.

Main Methods:

Comparative studies using model organisms
Cell biology techniques
Analysis of cell signaling pathways
Medical genetics research

Main Results:

Significant advancements in understanding cilium structure and function.

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Related Experiment Videos

Last Updated: May 26, 2026

In vivo Evaluation of Mucociliary Clearance in Mice

In vivo Evaluation of Mucociliary Clearance in Mice

Published on: December 18, 2020

Observation of the Ciliary Movement of Choroid Plexus Epithelial Cells Ex Vivo

Observation of the Ciliary Movement of Choroid Plexus Epithelial Cells Ex Vivo

Published on: July 13, 2015

Using Primary Neurosphere Cultures to Study Primary Cilia

Using Primary Neurosphere Cultures to Study Primary Cilia

Published on: April 14, 2017

Identification of the cilium's critical role in signaling and sensory pathways.

Mapping of cilium distribution within vertebrates.

Conclusions:

The vertebrate cilium is a key player in biological processes.
Dysfunction of this organelle leads to various pathologies.