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Related Concept Videos

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Venous Thrombosis III: Interprofessional Care

Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
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Venous Thrombosis IV: Nursing Management

Nursing management begins with a thorough assessment of the patient's health history. Key factors include trauma to veins, peripherally inserted central catheters, varicose veins, recent pregnancy or childbirth, surgery, bacteremia, prolonged bed rest, atrial fibrillation, COPD, heart failure, cancer, coagulation disorders, myocardial infarction, spinal cord injury, stroke, prolonged travel, recent bone fractures, and dehydration. Review medication intake, particularly oral contraceptives,...
Disorders of Hemostasis01:24

Disorders of Hemostasis

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Thromboembolic Disorders
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Related Experiment Video

Updated: May 26, 2026

External Cephalic Version: Is it an Effective and Safe Procedure?
08:49

External Cephalic Version: Is it an Effective and Safe Procedure?

Published on: June 6, 2020

Thrombophylaxis and bleeding complications after cesarean section.

Claudia A Snijder1, Jerôme M W Cornette, Wim C J Hop

  • 1Department of Obstetrics and Gynecology, Erasmus University Medical Center, Dr. Molewaterplein 60, Rotterdam, the Netherlands.

Acta Obstetricia Et Gynecologica Scandinavica
|January 11, 2012
PubMed
Summary

Different low molecular weight heparin (LMWH) regimens for cesarean section thromboprophylaxis impact bleeding complications. Nadroparin 5700IU showed higher bleeding rates, influencing postpartum safety.

Related Experiment Videos

Last Updated: May 26, 2026

External Cephalic Version: Is it an Effective and Safe Procedure?
08:49

External Cephalic Version: Is it an Effective and Safe Procedure?

Published on: June 6, 2020

Area of Science:

  • Obstetrics and Gynecology
  • Thrombosis and Hemostasis
  • Pharmacology

Background:

  • Cesarean section is a common surgical procedure.
  • Thromboprophylaxis with low molecular weight heparins (LMWHs) is standard for preventing venous thromboembolism in cesarean section patients.
  • Different LMWH regimens may have varying safety profiles regarding bleeding complications.

Purpose of the Study:

  • To evaluate the safety of different low molecular weight heparin (LMWH) thromboprophylaxis regimens in women undergoing cesarean section.
  • To compare the incidence of postoperative bleeding complications among distinct LMWH administration protocols.

Main Methods:

  • Retrospective, single-center, cross-sectional study.
  • Inclusion of 1527 women who underwent cesarean section and received thromboprophylaxis between 2004 and 2007.
  • Analysis of three consecutive thromboprophylaxis regimens: dalteparin 5000IU (group A), nadroparin 5700IU (group B), and nadroparin 2850IU (group C).

Main Results:

  • Group B (nadroparin 5700IU) exhibited a significantly higher incidence of bleeding complications requiring treatment compared to groups A and C (19/574 vs. 9/647 and 1/306, respectively).
  • These findings remained significant after adjusting for confounders like maternal age, BMI, and preeclampsia.
  • No significant difference in the incidence of thromboembolism was observed across the three groups.

Conclusions:

  • The choice of LMWH regimen for thromboprophylaxis in cesarean section significantly influences the risk of postoperative bleeding complications.
  • Nadroparin 5700IU regimen was associated with an increased risk of bleeding complications.
  • Optimizing LMWH protocols is crucial for enhancing maternal safety during the postpartum period.