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A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
Melanoma in 2011: a new paradigm tumor for drug development
Alexander M M Eggermont1, Caroline Robert
1Institut de Cancérologie Gustave Roussy, 114 Rue Edouard Vaillant, 94805 Villejuif, Paris-Sud, France. alexander.eggermont@igr.fr
Nature Reviews. Clinical Oncology
|January 11, 2012
Abstract:
Melanoma has emerged as the paradigm tumor for drug development through mutation-targeted therapies (inhibitors targeting BRAF, MEK, and c-KIT) and immunotherapy. Exploring the combinations of both approaches is a challenge that will require scientific rationale and the cooperation of the pharmaceutical industry. But, with these challenges comes another opportunity to change the paradigms in drug development.

