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Published on: October 6, 2020
Side-to-side neurorrhaphy for high-level peripheral nerve injuries
ShaoCheng Zhang1, Fang Ji, DaKe Tong
1Orthopedics Department, Changhai Hospital, 168 Changhai Road, Shanghai, China.
Acta Neurochirurgica
|January 11, 2012
Summary
Side-to-side neurorrhaphy shows promise for high-level peripheral nerve injuries. This technique achieved a 60% motor and 100% sensory useful recovery rate without significant donor nerve loss.
Area of Science:
- Neurosurgery
- Regenerative Medicine
- Peripheral Nerve Injury
Background:
- Peripheral nerve repair outcomes for high-level injuries remain unsatisfactory.
- Side-to-side neurorrhaphy, developed between 1994-2002, involves suturing an injured nerve to a donor nerve.
- This study evaluates the clinical efficacy of this technique for severe nerve injuries.
Purpose of the Study:
- To assess the clinical results of side-to-side neurorrhaphy in patients with high-level peripheral nerve injuries.
- To determine the functional recovery rates following this surgical intervention.
Main Methods:
- Twenty-five patients with high-level peripheral nerve injuries underwent side-to-side neurorrhaphy.
- Nerve function recovery was evaluated using the British Medical Research Council (BMRC) scale.
- Follow-up averaged 3.2 years.
Main Results:
- A useful recovery rate (BMRC grade ≥3) of 60% for motor function and 100% for sensory function was observed.
- Post-surgery scores ranged from M2/S3 to M3/S4.
- No significant loss of donor nerve function was reported.
- Injury type and time to surgery correlated with motor recovery, while age, gender, and nerve location did not.
Conclusions:
- Side-to-side neurorrhaphy is a promising and feasible method for repairing high-level peripheral nerve injuries.
- The technique demonstrates significant potential for restoring both motor and sensory function.

