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[Visual evoked potential abnormalities in a girl with brain stem encephalitis (Bickerstaff)]
No to Hattatsu = Brain and Development
|September 1, 1990
Summary
A pediatric case study shows transient ophthalmoplegia and consciousness disturbance. Visual evoked potentials (VEPs) revealed temporary abnormalities, normalizing over twelve months, indicating potential neuroplasticity.
Area of Science:
- Neuroscience
- Pediatric Neurology
- Ophthalmology
Background:
- A 16-month-old girl presented with acute bilateral ophthalmoplegia, ptosis, and altered consciousness, suggesting a possible central nervous system insult.
- Cranial CT revealed non-specific brain atrophy, and auditory brainstem responses were normal, ruling out significant brainstem or auditory pathway dysfunction.
Observation:
- Serial Visual Evoked Potentials (VEPs) were performed to assess visual pathway function during the acute and recovery phases.
- Initially, no significant VEP patterns were observed during the acute stage of the illness.
Findings:
- Three months post-onset, VEPs demonstrated asymmetrical abnormalities, specifically left-sided deficits including an unidentifiable P100 wave.
- These VEP abnormalities gradually diminished by six months and normalized bilaterally by twelve months.
Implications:
- This case highlights the dynamic nature of visual pathway dysfunction in pediatric neurological conditions.
- Serial VEP monitoring can be a valuable tool for tracking recovery and assessing neuroplasticity in children following acute neurological events.