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Updated: May 26, 2026

Generation and Control of Electrohydrodynamic Flows in Aqueous Electrolyte Solutions
Published on: September 7, 2018
[Characteristics of electroosmotic flow in open-tubular capillary electrochromatography with magnetic nanoparticle
Sasa Qin1, Chaoran Zhou, Yaxian Zhu
1Shanghai Key Laboratory of Functional Materials Chemistry, East China University of Science a Technology, Shanghai 200237, China.
Abstract:
A novel open-tubular capillary electrochromatography (OT-CEC) column with magnetic nanoparticle coating as mixed-mode stationary phase was prepared. The mixed-mode stationary phases were obtained by mixing C18 and amino modified magnetic nanoparticles with different ratios. The mixed modified magnetic nanoparticles as stationary phase were introduced into the capillary by using external magnetic force. The magnetic nanoparticle coating can be easily regenerated by removing the external magnetic field, and applied to other separation modes. The characteristics of electroosmotic flow (EOF) were theoretically investigated through the effect of physicochemical properties of different stationary phases on EOF. The experiment was conducted under different ratios of mixed-mode stationary phases and coating lengths, and it was verified that the theoretical conclusions accorded with the experimental results. It was shown that the EOF can be easily adjusted by changing the ratio of stationary phases or the number of permanent magnets.
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