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Multiple focal nodular hyperplasia, an incidental finding on autopsy
Jyothi B Shetty1, Anjali D Amrapurkar, Asha S Shenoy
1Department of Pathology, T.N. Medical College and B Y L Nair Ch. Hospital, Mumbai, India. jyotibshetty@yahoo.com
Indian Journal of Pathology & Microbiology
|January 12, 2012
Summary
Focal nodular hyperplasia (FNH), a benign liver condition, can present diagnostic challenges. This case highlights multiple FNH lesions found incidentally during autopsy, emphasizing the need for histopathology when gross examination is inconclusive.
Area of Science:
- Hepatology
- Pathology
- Radiology
Background:
- Focal nodular hyperplasia (FNH) is a common benign liver lesion.
- Diagnostic challenges persist despite FNH being well-described.
- Incidental radiological findings are typical for FNH.
Observation:
- A case of multiple FNH in a 23-year-old male is presented.
- Lesions were discovered incidentally during autopsy.
- Gross examination did not initially suggest FNH due to atypical presentation (multiple lesions, absent central scar).
Findings:
- Histopathological examination of multiple sections confirmed the diagnosis of FNH.
- The absence of a central scar in multiple lesions complicated initial gross assessment.
Implications:
- This case underscores the importance of histopathology in diagnosing FNH, especially in atypical presentations.
- It highlights potential diagnostic difficulties in distinguishing FNH from other liver pathologies based solely on gross morphology.
- Further research into the imaging and pathological spectrum of FNH may be warranted.
