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Related Experiment Video

Updated: May 25, 2026

Non-Intubated Video-Assisted Thoracoscopic Surgery

Non-Intubated Video-Assisted Thoracoscopic Surgery

Published on: May 26, 2023

Preventing post-thoracotomy pain syndrome.

Yury Khelemsky¹, Christopher J Noto

¹Department of Anesthesiology, Mount Sinai School of Medicine, New York, NY, USA. yury.khelemsky@mountsinai.org

The Mount Sinai Journal of Medicine, New York

|January 13, 2012

Summary

Post-thoracotomy pain syndrome remains a challenge, with limited evidence supporting current prevention and treatment interventions. Further research into underlying mechanisms and well-designed trials are crucial for effective management.

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Last Updated: May 25, 2026

Non-Intubated Video-Assisted Thoracoscopic Surgery

Non-Intubated Video-Assisted Thoracoscopic Surgery

Published on: May 26, 2023

Area of Science:

Thoracic surgery
Pain management
Anesthesiology

Background:

Post-thoracotomy pain syndrome (PTPS) is a common complication following chest surgery.
The exact pathophysiological mechanisms of chronic post-surgical pain are not fully understood.
Current interventions for PTPS lack definitive evidence of efficacy.

Purpose of the Study:

To review anesthetic and surgical factors influencing PTPS incidence.
To explore the effectiveness of existing treatments for PTPS.
To highlight the need for further research in PTPS prevention and management.

Main Methods:

Literature review of studies investigating anesthetic and surgical factors.
Exploration of procedural and pharmacological interventions for PTPS.
Analysis of the current evidence base for PTPS management.

Main Results:

Anesthetic and surgical factors have been investigated, but conclusive evidence is lacking.
Various interventions show potential but require further validation.
Definitive studies are needed to establish effective prevention and treatment strategies.

Conclusions:

Effective prevention and treatment of post-thoracotomy pain syndrome require further investigation.
Elucidating the underlying pathophysiological mechanisms is essential.
Well-designed clinical trials are necessary to evaluate novel therapeutic agents for PTPS.