Echocardiographic impact of hydration status in dialysis patients
Isabel Juan-García1, María J Puchades, Rafael Sanjuán
1Nefrología, Hospital Clínico Universitario De Valencia, Valencia, Valencia, España. ijuangar@hotmail.com
Insights
Overhydration is common in dialysis patients, particularly before hemodialysis. Bioimpedance effectively identifies overhydrated individuals, revealing correlations between hydration status and echocardiographic changes like left ventricular hypertrophy.
Area of Science:
- Nephrology
- Cardiology
- Medical Diagnostics
Background:
- Cardiovascular disease is the leading cause of mortality in Chronic Kidney Disease (CKD) patients.
- Left ventricular hypertrophy (LVH) is a common manifestation in CKD, associated with hypertension and overhydration.
- Understanding hydration status is crucial for managing cardiovascular risk in dialysis patients.
Purpose of the Study:
- To stratify patients undergoing dialysis based on their hydration status.
- To evaluate echocardiographic alterations in different hydration groups.
- To assess the utility of bioimpedance in identifying overhydration.
Main Methods:
- A cross-sectional study involving 117 dialysis patients (65 hemodialysis, 52 peritoneal dialysis).
- Utilized multifrequency bioimpedance (BCM-Body Composition Monitor) to assess extracellular water to total body water (ECW/TBW) ratio.
- Performed transthoracic echocardiography and analyzed blood tests.
Main Results:
- Hemodialysis (HD) patients exhibited higher pre-dialysis overhydration (67.1%) compared to peritoneal dialysis (PD) patients (46.1%).
- Overhydration was linked to arterial hypertension in nearly half of the affected population.
- Left ventricular hypertrophy, particularly eccentric LVH, was more prevalent in overhydrated HD patients, correlating with elevated LAVI and ILVM.
Conclusions:
- Bioimpedance analysis is effective in detecting overhydrated patients within dialysis populations.
- Echocardiographic findings, including left atrial volume index (LAVI) and left ventricular mass index (LVMI), show a significant correlation with hydration status (ECW/TBW ratio).
- Hydration management is critical for mitigating cardiovascular complications in dialysis patients.
Introduction:
Cardiovascular disease is the main cause of death in Chronic Kidney Disease patients. Left ventricular hypertrophy is the most common manifestation and it is linked to arterial hypertension and overhydration. The goal of this paper is to stratify dialyzed patients according to hydration status and to make an evaluation about the possible echocardiography alterations of the different groups.
Methods:
A transversal study was carried out with 117 patients: 65 were on hemodialysis and 52 on peritoneal dialysis. We performed the following tests: multifrequency bioimpedance with the BCM-Body Composition Freesenius’ Monitor system, transthoracic echocardiography, and blood tests. If ECW/TBW (extracellular water vs total body water) normalization ratio for age and gender was > 2.5% SD, the patient was considered overhydrated.
Results:
HD patients are significantly overhydrated before HD (67.1%) compared to DP patients (46.1%), and almost half of the overhydrated population presents arterial hypertension. However, after an HD session, a better control of the hydration status is reached (26.1%). DP patients frequently present high arterial pressure and/or are under antihypertensive treatment (DP 76.9% vs HD 49.2%). Left ventricular hypertrophy is much more common in HD overhydrated patients, eccentric LVH being more prevalent. Overhydrated patients present significantly high values of LAVI, ILVM, OH/ECW.
Conclusions:
Bioimpedance technique allows for the detection of a large number of overhydrated patients. Echocardiographic alterations in dialyzed patients show a high correlation between the hydration stage by ECW/TBW normalized ratio for age and gender and the LAVI and ILVM.
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