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Updated: May 25, 2026

Annotation of Plant Gene Function via Combined Genomics, Metabolomics and Informatics
Published on: June 17, 2012
Identifying functional annotation for noncoding genomic sequences
Douglas P Mortlock1, Steven Pregizer
1Department of Molecular Physiology & Biophysics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Abstract:
The recent success of genome-wide association studies has generated a trove of biologically significant variants implicated in human disease. However, many, if not most, of these variants fall in noncoding regions that have traditionally lacked much functional annotation. New data sets and tools allow for a more detailed assessment of potential importance of noncoding genetic variants. An overview of types of regulatory annotation that are currently available, and approaches to analyzing this data are provided with emphasis on usage of the UCSC genome browser.
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