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Related Concept Videos

Antidepressant Drugs: MAOIs and Other Agents01:23

Antidepressant Drugs: MAOIs and Other Agents

Atypical antidepressants, including bupropion (Wellbutrin), mirtazapine (Remeron), nefazodone (Serzone), trazodone (Desyrel), and vilazodone (Viibryd), offer unique mechanisms of action. Bupropion weakly inhibits dopamine and norepinephrine reuptake, aiding depression treatment and smoking cessation, with a low risk of sexual dysfunction. Mirtazapine enhances serotonin and norepinephrine neurotransmission, leading to sedation, increased appetite, and weight gain. As a result, it helps treat...
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Antidepressant Drugs: Overview

Antidepressant drugs are a class of medications primarily used for treating various mood disorders, including major depression, anxiety disorders, and other related conditions. These medicines work by modulating the neurotransmitter balance within the brain, alleviating depressive symptoms. Antidepressants can be broadly categorized into several groups according to their mechanism of action and chemical structure: Selective Serotonin Reuptake Inhibitors (SSRIs), Serotonin-Norepinephrine...
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Cognitive Therapy

Cognitive therapy, pioneered by Aaron T. Beck in the 1960s, is a structured approach to addressing psychological distress by focusing on the influence of thoughts on emotions and behaviors. All cognitive therapies involve the basic assumption that human beings have control over their feelings, and that how individuals feel about something depends on how they think about it. Unlike psychoanalytic methods that delve into unconscious processes or humanistic approaches emphasizing...
Treatment Strategies for Psychological Disorders01:24

Treatment Strategies for Psychological Disorders

Treatment approaches for psychological disorders fall into three main categories: psychological, biological, and sociocultural. Each approach targets different aspects of mental health, requiring varying levels of education and training.
Psychological therapies focus on modifying emotions, thoughts, and behaviors through talking, interpreting, listening, rewarding, challenging, and modeling. Clinical psychologists, counselors, and social workers commonly practice psychotherapy. Clinical...
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Tricyclic Antidepressants (TCAs), including Desipramine (Norpramin), Imipramine (Tofranil), Clomipramine (Anafranil), and Amitriptyline (Elavil), inhibit serotonin and norepinephrine reuptake and also block other receptors. They are used for depression, pain conditions, and insomnia. Common adverse effects include anticholinergic effects, sedation, orthostatic hypotension, and weight gain. They have a narrow therapeutic window and so require plasma-level monitoring. Abrupt discontinuation can...
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Drug Therapy

The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
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Vagus Nerve Stimulation As an Adjunctive Neurostimulation Tool in Treatment-resistant Depression
04:29

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Published on: January 7, 2019

Using algorithms and computerized decision support systems to treat major depression.

Richard C Shelton1, Madhukar H Trivedi

  • 1Department of Psychiatry, Vanderbilt School of Medicine, Nashville, Tennessee, USA.

The Journal of Clinical Psychiatry
|January 17, 2012
PubMed
Summary

Computerized decision support systems (CDSS) can help clinicians adhere to major depressive disorder treatment guidelines by overcoming barriers like time constraints. Integrating CDSS with electronic health records enhances accessibility and adherence to evidence-based care.

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Area of Science:

  • Psychiatry
  • Medical Informatics

Background:

  • Major depressive disorder treatment guidelines recommend measurement-based care and algorithms for improved patient outcomes.
  • Clinicians face barriers to guideline adherence, including time constraints, lack of support, and perceived algorithm inflexibility.

Discussion:

  • Computerized decision support systems (CDSS) offer a solution to increase adherence to clinical guidelines.
  • CDSS can provide accessible, user-friendly measurement-based care strategies.
  • These systems can individualize treatment and deliver guideline information at the point of care.

Key Insights:

  • CDSS integration into electronic health records can simplify implementation.
  • User-friendly design and point-of-care information delivery are crucial for CDSS effectiveness.
  • Addressing practical barriers is key to improving guideline adherence in mental health treatment.

Outlook:

  • Future research should focus on the long-term impact of CDSS on patient outcomes in major depressive disorder.
  • Optimizing CDSS for seamless EHR integration is essential for widespread adoption.
  • Exploring patient perspectives on CDSS-supported treatment decisions will be valuable.