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Updated: May 25, 2026

Neisseria meningitidis Infection of Induced Pluripotent Stem-Cell Derived Brain Endothelial Cells
Published on: July 14, 2020
[Mycoplasma pneumoniae encephalitis associated with basal ganglia necrosis]
N El Hafidi1, B Allouch, F Benbrahim
1Service de pathologie infectieuse et de pneumo-allergologie pédiatrique, hôpital Enfant Rabat, rue Famfdal Cherkaoui Rabat-Instituts, BP 6527, Rabat, Morocco.
Introduction:
Severe central nervous system diseases, such as encephalitis, have been reported in association with Mycoplasma pneumoniae infections.
Case Report:
A previously healthy 5-year-old boy presented with an atypical pneumonia; he rapidly developed encephalitis revealed by lethargy, generalized status epilepticus. MRI showed abnormal signals in the basal ganglia, typical of bilateral striatal necrosis. Serologic tests for M. pneumoniae were positive, the child recovered almost completely.
Conclusion:
M. pneumoniae infection should be considered in all cases of acute encephalopathy; yet the pathogenesis of the disorder is unknown and the treatment uncertain.
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